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ProteomicsMachine learning for grading and prognosis of esophageal dysplasia using mass spectrometry and histological imaging
Background: Barrett’s esophagus (BE) is a precursor lesion of esophageal adenocarcinoma and may progress from non-dysplastic through low-grade dysplasia (LGD) to high-grade dysplasia (HGD) and cancer. Grading BE is of crucial prognostic value and is currently based on the subjective evaluation of bi...
ORGANISM(S): Homo sapiens (Human) 
2021-11-15 | PXD028949 | Pride
Deep learning Mass spectrometry imaging H&e staining Barrett’s esophagus Machine learning 
TranscriptomicsMarker gene discovery for Staphylococcus epidermidis infection in zebrafish embryos (Agilent)
We use the zebrafish embryo model to study the innate immune response against Staphylococcus epidermidis. Therefore, we injected S. epidermidis (and three controls groups) into the yolk at 2 hpf and samples at mutiple timepoints. Gene expression profiles were obtained at 6, 30, 54, 78, 102 and 126 h...
ORGANISM(S): Danio rerio 
2013-04-01 | E-GEOD-37227 | biostudies-arrayexpress
TranscriptomicsSpecificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection
Pathogenic mycobacteria have the ability to survive within macrophages and persist inside granulomas composed of host immune cells. The complex host-pathogen interactions that determine the outcome of a mycobacterial infection process result in marked alterations of the host gene expression profile....
ORGANISM(S): Danio rerio 
2010-05-15 | E-GEOD-15328 | biostudies-arrayexpress
UnknownIdentifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach.
Not available
S-EPMC4833164 | biostudies-literature
UnknownEarly onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
Not available
S-EPMC2880297 | biostudies-literature
UnknownDevelopment of Kinase Inhibitors via Metal-Catalyzed C⁻H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies.
Not available
S-EPMC6225322 | biostudies-literature
TranscriptomicsTraf6 function in the innate immune response of zebrafish embryos
Transcriptional profiling of the zebrafish embryonic host response to a systemic bacterial infection with Salmonella typhimurium (strain SL1027); comparison between traf6 knock-down and control morpholino treated embryos. All infection experiments were performed using mixed egg clutches of ABxTL str...
ORGANISM(S): Danio rerio 
2010-08-01 | E-GEOD-21024 | biostudies-arrayexpress
UnknownThe B. subtilis Rok protein is an atypical H-NS-like protein irresponsive to physico-chemical cues.
Not available
S-EPMC9757077 | biostudies-literature
TranscriptomicsTraf6 function in the innate immune response of zebrafish embryos
Transcriptional profiling of the zebrafish embryonic host response to a systemic bacterial infection with Salmonella typhimurium (strain SL1027); comparison between traf6 knock-down and control morpholino treated embryos. Two-way factorial dual colour design with factor 1 'infection with Salmonella ...
ORGANISM(S): Danio rerio 
2010-08-01 | E-GEOD-20310 | biostudies-arrayexpress
UnknownHeterogeneity of rhythmic suprachiasmatic nucleus neurons: Implications for circadian waveform and photoperiodic encoding.
Not available
S-EPMC307681 | biostudies-literature
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