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TranscriptomicsTranscription profiling by array of eWAT from CD1 WT and Irx5-KO mice fed a high fat diet
The aim was to compare the global gene expression of epididymal white adipose tissue (eWAT) of WT and Irx5-KO mice. Mice 10 weeks of age were fed a high-fat diet for 10 weeks before eWAT was dissected out, RNA extracted and microarray performed
ORGANISM(S): Mus musculus 
2018-12-12 | E-MTAB-6726 | biostudies-arrayexpress
TranscriptomicsMicroarray of isolated adipocytes from subcutaneous adipose tissue of severely obese patients compared to lean controls
The aim of the project was to compare global gene expression in adipocytes from obese patients and lean controls. Subcutaneous adipose tissue was collected from severely obese patients undergoing bariatric surgery (average body-mass index (BMI) of 45.5 kg/m2 (n = 12, thereof 4 men) and healthy lean...
ORGANISM(S): Homo sapiens 
2018-12-12 | E-MTAB-6728 | biostudies-arrayexpress
TranscriptomicsIndividual SRC-2 and SRC-3 knock-down in MCF-7 cells
Experimental aim: identification of SRC-2 and SRC-3-related genes in MCF-7 breast cancer cells. Experimental workflow: 1. shRNA transduction. MCF-7 cells were transduced with a mix of lentiviral particles containing five individual lentiviral pLKO.1-puro short hairpin (sh) RNA plasmids targeting dif...
ORGANISM(S): Homo sapiens 
2019-07-01 | E-MTAB-7018 | biostudies-arrayexpress
ProteomicsSerum proteome in metastatic breast cancer patients
We identified 967 proteins among 75 serum samples from patients with BC. Among these, 39 proteins were altered in serum samples at diagnosis, between progressors and non-progressors. Among these, 4 proteins were further altered when the progressors developed distant metastasis. In addition, within p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-03-07 | MSV000094255 | MassIVE
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