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TranscriptomicsAnalysis of ETS gene expression patterns uncovers novel ETS mediated gene silencing pathways in prostate cancers
Deregulated expression of ETS transcription factors with oncogenic and tumor suppressor function occurs frequently in prostate cancer leading to profound alterations of the cancer transcriptome. By integrating genomic and functional studies we identified key targets of the aberrantly expressed ETS ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-14206 | biostudies-arrayexpress
TranscriptomicsReduced expression of RhoE promotes ROCK-dependent invasion in transformed human fibroblasts
Cen3tel cells, obtained by telomerase immortalization of human fibroblasts, gradually underwent neoplastic transformation and became metastatic in immunocompromised mice. Neoplastic transformation was associated with a change in cell morphology (from fibroblastic to polygonal). Tumorigenic cells acq...
ORGANISM(S): Homo sapiens 
2011-04-20 | E-GEOD-15742 | biostudies-arrayexpress
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