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UnknownClinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis).
Not available
S-EPMC5455706 | biostudies-literature
TranscriptomicsNHGRI_Sarcoma_Baird
Sarcomas are a biologically complex group of tumors of mesenchymal origin. By using gene expression microarray analysis, we aimed to find clues into the cellular differentiation and oncogenic pathways active in these tumors as well as potential biomarkers and therapeutic targets. We examined 181 tum...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-2553 | biostudies-arrayexpress
TranscriptomicsAnalyses of Human Brain Metastases of Breast Cancer Reveal the Association between HK2 Up-Regulation and Poor Prognosis
Analyses of Resected Human Brain Metastases of Breast Cancer Reveal the Association between Up-Regulation of Hexokinase 2 and Poor Prognosis. Brain metastases of breast cancer seem to be increasing in incidence as systemic therapy improves. Metastatic disease in the brain is associated with high mor...
ORGANISM(S): Homo sapiens 
2010-01-21 | E-GEOD-20016 | biostudies-arrayexpress
UnknownMolecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.
Not available
S-EPMC4356709 | biostudies-literature
GenomicsGenome-wide map of PAX3-FKHR binding sites in rhabdomyosarcoma
We report the genome-wide maps of PAX3-FKHR binding sites. Chromatin immunoprecipitation was performed against PAX3-FKHR positive (Rh4) and PAX3-FKHR negative (RD) rhabdomyosarcoma cells with a monoclonal antibody (pFM2) specific for the fusion region of PAX3-FKHR. We obtained 4 million sequence t...
ORGANISM(S): Homo sapiens 
2010-08-17 | E-GEOD-19063 | biostudies-arrayexpress
TranscriptomicsLymph nodes with follicular lymphoma or reactive hyperplasia
Comparison of gene expression profiles of follicular lymphoma vs. reactive lymph nodes. 8 cases of follicular lymphoma; 5 cases of reactive lymph nodes.
ORGANISM(S): Homo sapiens 
2011-09-26 | E-GEOD-14214 | biostudies-arrayexpress
TranscriptomicsGene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast
Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...
ORGANISM(S): Homo sapiens 
2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress
TranscriptomicsCopy number aberrations of genes regulating normal thymus development in thymic epithelial tumors
Thymic epithelial tumors are a group of neoplasms with heterogeneous histological features and clinical behavior. The identification of markers useful to predict patient prognosis and molecular targets for therapies is limited by a very little understanding of the biology of these neoplasms. We eval...
ORGANISM(S): Homo sapiens 
2013-05-03 | E-GEOD-23540 | biostudies-arrayexpress
UnknownPhase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma.
Not available
S-EPMC3532390 | biostudies-literature
TranscriptomicsMouse Models of Alveolar/Embryonal Rhabdomyosarcoma & Spindle Cell Sarcomas
A series of conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were generated and validated for relavence to corresponding human cancers. Conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma...
ORGANISM(S): Mus musculus 
2011-02-17 | E-GEOD-22520 | biostudies-arrayexpress
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