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xref:PubMed:40940409 (1)
xref:PubMed:33338421 (1)
xref:PubMed:41797907 (1)
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The membrane curvature-inducing REEP1-4 proteins generate an ER-derived vesicular compartment

The endoplasmic reticulum (ER) is shaped by abundant membrane curvature-generating proteins that include the REEP family member REEP5. The REEP1 subfamily, consisting of REEP1-4 in mammals, is less abundant and lacks a N-terminal region. Mutations in REEP1 and REEP2 cause Hereditary Spastic Parapleg...

ORGANISM(S): Homo sapiens (Human)

2025-01-18 | PXD055950 | Pride

Proteome data for unbiased curvature-gradient proteomics reveals anti-curvature sensors

The results contain measurements of protein interacting with membranes of three different curvatures (positive, negative, and zero curvature).

ORGANISM(S): Homo Sapiens (human)

2026-09-10 | PXD078093 | JPOST Repository

A conserved membrane curvature-generating protein is crucial for autophagosome formation in fission yeast

Organelles are shaped by curvature-generating proteins, which include the reticulons and REEPs that are involved in forming the endoplasmic reticulum (ER). A conserved REEP subfamily differs from the ER-shaping REEPs in abundance and membrane topology and has unidentified functions. Here, we show th...

ORGANISM(S): Schizosaccharomyces pombe 927

2023-08-06 | PXD043260 | Pride

Reep1 Autophagy Fission yeast

Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair.

Not available

S-EPMC5696365 | biostudies-literature

Interplay of membrane crosslinking and curvature induction by annexins.

Not available

S-EPMC9800579 | biostudies-literature

Transmembrane proteins tetraspanin 4 and CD9 sense membrane curvature.

Not available

S-EPMC9618112 | biostudies-literature