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The goal of the project was to identify risk alleles that are associated with recurrence of membranous nephropathy in the graft after kidney transplantation. First, we sequenced PLA2R1 and HLA-D loci in 248 patients with primary membranous nephropathy and identified two independent single nucleotide...
GWAS for Membranous Nephropathy
GWAS for Membranous Nephropathy
Total 1,427 differentially expressed proteins were identified between the MN and HC groups. KEGG pathway analysis showed significant enrichment of these DEPs in the complement-activated pathway within the MN group. Additionally, a correlation was found between proteinuria and the levels of 27 urinar...
ORGANISM(S): Homo Sapiens 
2025-02-01 | PXD060494 |
Background: Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-based proteomics. However, the antigenic targets of disease are unknown for >10% of MN and >50% of membranous lupus nephritis (MLN) cases. We identified multiple new targets in PLA2R-/THSD7A-/EXT-/NELL1-q...
ORGANISM(S): Homo sapiens (Human) 
2023-04-06 | PXD035854 | Pride
Background: Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-based proteomics. However, the antigenic targets of disease are unknown for >10% of MN and >50% of membranous lupus nephritis (MLN) cases. We identified multiple new targets in PLA2R-/THSD7A-/EXT-/NELL1-q...
ORGANISM(S): Homo sapiens (Human) 
2023-04-06 | PXD035853 | Pride
Idiopathic membranous nephropathy and minimal change disease (MCD) transcriptome
Single-cell sequencing reveals the immune cell landscape of peripheral blood mononuclear cells in primary membranous nephropathy
Genomics
WT1 mutation-associated membranous nephropathy
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