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TranscriptomicsInterrogation of global mutagenesis data with a genome scale model of Neisseria meningitidis to assess gene fitness in vitro and in sera.
Background Neisseria meningitidis is an important human commensal and pathogen that causes several thousand deaths each year, mostly in young children. How the pathogen replicates and causes disease in the host is largely unknown, particularly the role of metabolism in colonization and disease. Com...
ORGANISM(S): Neisseria meningitidis 
2012-01-23 | E-BUGS-129 | biostudies-arrayexpress
ProteomicsMycobacterium tuberculosis VadK required for regulation of the methylcitrate cycle and virulence
We performed co-immunoprecipitation experiments using WT Mtb transformed with a plasmid encoding a FLAG-tagged VadK under a constitutive promoter (VadKMtb). We immunoprecipitated from whole cell lysates of WT and VadKMtb grown in standard 7H9 media with and without propionate to identify interaction...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Bacteria 
2026-03-19 | PXD073941 | Pride
Metabolism Virulence Mycobacterium tuberculosis Regualtion Kinase 
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