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UnknownCorticotropin-releasing Factor Changes the Phenotype and Function of Dendritic Cells in Mouse Mesenteric Lymph Nodes.
Not available
S-EPMC4622140 | biostudies-literature
ProteomicsUbiquitin Thioesterase OTUB2 is An Endoplasmic Reticulum Stress-associated β Cell Autoantigen Targeted by CD8+ T cells in Type 1 Diabetes
Autoreactive CD8+ T cell plays a key role in the pathogenesis of Type 1 diabetes (T1D), but the antigen spectrum that activate autoreactive CD8+ T cells is still not completely clear. Endoplasmic reticulum stress（ERS）has been implicated in the generation of β cell autoantigens and the enhanced immun...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD041227 | Pride
Otub2 Endoplasmic reticulum stress Type 1 diabetes Cd8+ t-cell. 
ProteomicsProteome of uterine cavity fluid in female rattus
The injection with GnIH/saline through the lateral ventricle. At 6 h after injection, the protein components of rats in the experimental and control groups were analyzed using Liquid Chromatography (LC)-Mass Spectrometry (MS)/MS.
ORGANISM(S): Rattus Rattus 
2022-10-31 | PXD037826 |
GenomicsA Comprehensive Catalogue of Somatic Mutations from a Human Cancer Genome
We have carried out complete sequencing of the genome of the human male maligant melanoma cell line COLO-829 using the Illumina Genome Analyzer II. We generated a sequencing library with a median insert size of ~200 bp following random fragmentation and gel fractionation of the genomic DNA. We seque...
EGAS00000000052 | EGA
GenomicsEGAD00000000054
NCI-H209 is an immortal cell line derived from a bone marrow metastasis of a patient with small cell lung cancer, taken before chemotherapy. The specimen showed histologically typical small cells with classic neuroendocrine features. NCI-BL209 is an EBV-transformed B-cell line derived from the same ...
EGAD00000000054 | EGA
GenomicsA small cell lung cancer genome reports complex tobacco exposure signatures
Cancer is driven by mutation. Worldwide, tobacco smoking is the major lifestyle exposure that causes cancer, exerting carcinogenicity through 60 chemicals that bind and mutate DNA. Using massively parallel sequencing technology, we sequenced a small cell lung cancer cell line, NCI-H209, to explore t...
EGAS00000000051 | EGA
ProteomicsProteomics of cardiac tissue of mice after sepsis model
Dysregulated cardiac function after sepsis is common in intensive care unit (ICU) and known to predict poor long-term outcome and increase mortality. Effective therapeutic strategies are largely lacking. Moreover, the pathological feature and the molecular mechanism underlying cardiac dysfunction in...
ORGANISM(S): Mus Musculus 
2023-04-14 | PXD041530 |
GenomicsEGAD00000000055
COLO-829 is a publicly available immortal cancer cell line and COLO-829BL is a lymphoblastoid cell line derived from the same patient
EGAD00000000055 | EGA
ProteomicsNociceptive neurons inhibit neutrophil extracellular trap formation via MLKL-licensed histone release
This data set contains the raw data of proteinomic analysis of dorsal root ganglions (DRGs) in WT and MLKL-KO mice under basal condition and after CFA treatment, and MLKL-based IP-MS analysis of WT DRGs under basal condition and after CFA treatment.
ORGANISM(S): Mus Musculus 
2026-04-16 | PXD077273 |
ProteomicsThe Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium
Bidirectional signal transduction between tumor epithelial cells and tumor microenvironment (TME) is important for tumor development. Here we showed that Lin28b/let-7 pathway is indispensable for modulating the expression of Wnt5a in tumor epithelium, which could be secreted and then up-regulates Li...
ORGANISM(S): Mus Musculus 
2023-09-19 | PXD045477 |
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