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UnknownEvaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid.
Not available
S-EPMC4981784 | biostudies-literature
TranscriptomicsPTEN loss deM-oM-,M-^Anes a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) represents a heterogeneous diagnostic category with distinct molecular subtypes that can be deM-oM-,M-^Aned by gene expression proM-oM-,M-^Aling. However, even within these deM-oM-,M-^Aned subtypes, heterogeneity prevails. To further elucidate the pathogenesis o...
ORGANISM(S): Homo sapiens 
2013-07-09 | E-GEOD-45495 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Dahl salt-sensitive and salt-resistant congenic rats
Kidney samples from three Dahl Salt-sensitive S rats were compared with kidney samples from three S.R(9)x3A congenic rats.
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1775 | biostudies-arrayexpress
TranscriptomicsGEP of PMBCs during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer (RCC) patients
Tumor-induced immunosuppression remains a major challenge for immunotherapy of cancer patients. To further elucidate why an allogeneic gene-modified (Interleukin-7(IL-7)/CD80 co-transfected) renal cell cancer vaccine failed to induce clinically relevant TH1-polarized immune responses, peripheral blo...
ORGANISM(S): Homo sapiens 
2014-09-24 | E-GEOD-51490 | biostudies-arrayexpress
TranscriptomicsLncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [ChIRP-seq]
While thousands of long non-coding RNAs (lncRNAs) are expressed in higher eukaryotes, the potential regulatory roles of lncRNAs in regulated gene transcription programs remain rather poorly understood. Here, we report that two lncRNAs highly overexpressed in aggressive prostate cancer, PRNCR1 and PC...
ORGANISM(S): Homo sapiens 
2013-08-15 | E-GEOD-47804 | biostudies-arrayexpress
GenomicsGenome-wide maps of Egr2 transcription factor binding sites in NKT and anti TCRb injected thymocytes.
We report the application of single-molecule-based sequencing technology for mapping the Egr2 transcriptional program in developing thymic NKT. We found that Egr2 controls the induction of genes required for NKT development. Examination of developing NKT cells and thymocytes receiving a strong TCR s...
ORGANISM(S): Mus musculus 
2012-02-06 | E-GEOD-34254 | biostudies-arrayexpress
ProteomicsProteome-Wide Characterization of Phosphorylation-Induced Conformational and Stability Changes in Breast Cancer
Large-scale studies of protein phosphorylation have generally focused on determining the sites and stoichiometry of phosphorylated proteins derived from different biological specimens such as cell lines and tissue samples. While such information is important for understanding the role of phosphoryla...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD007916 | Pride
Protein stability Phosphorylation Human breast cancer Protein conformation 
ProteomicsLarge-Scale Characterization of Phosphorylation-Induced Conformational and Stability Changes in Breast Cancer
Large-scale studies of protein phosphorylation have generally focused on determining the sites and stoichiometry of phosphorylated proteins derived from different biological specimens such as cell lines and tissue samples. While such information is important for understanding the role of phosphoryla...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD007878 | Pride
Protein stability Phosphorylation Human breast cancer Protein conformation 
ProteomicsChemical Denaturation and Protein Precipitation (CPP) on E. coli lysate
Chemical Denaturation and Protein Precipitation (CPP) was performed on an E. coli lysate in order to determine the precipitaiton midpoint for the proteome
ORGANISM(S): Escherichia coli 
2023-01-03 | PXD036219 | Pride
Cpp E. coli Precipitation 
ProteomicsEffect of rumen-protected methionine on metabolic profile in liver, muscle and blood serum samples of growing German Simmental bulls at restricted protein supply
This study aimed to determine the metabolic response of growing Fleckvieh bulls fed diets low in crude protein (CP) supplemented with rumen-protected methionine (RPM). In total, 69 bulls were assigned to three dietary treatments (n=23/group): Positive control (CON; 13.7% CP; 2.11 g methionine/kg DM...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2023-07-07 | MSV000092367 | MassIVE
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