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Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
Metastatic ability correlates well with the malignance of esophageal squamous cell carcinoma (ESCC). Gaps remain in elucidating the multi-layered interaction networks during ESCC metastasis in the premise of lysine lactylation (Kla) is of crucial importance. Here, we performed an integrated proteoge...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD063341 | Pride
Soluble aggregates of the microtubule-associated protein tau have been challenging to assemble and characterize, despite their important role in the development of tauopathies. We found that sequential hyperphosphorylation by protein kinase A in conjugation with either glycogen synthase kinase 3beta...
ORGANISM(S): Homo sapiens (Human) 
2022-04-13 | PXD033127 | Pride
The present study employs Liquid Chromatography-Mass Spectrometry (LC-MS) technology for the identification of proteins, utilizing the Q-Exactive mass spectrometer produced by Thermo Fisher Scientific. Upon the analysis of the ARP1-USP13-OE sample via Proteome Discoverer software, a total of 3631 pe...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD057487 | Pride
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