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TranscriptomicsGenomic landscape of meningiomas
This SuperSeries is composed of the following subset Series: GSE16581: Genomic landscape of meningiomas: gene expression GSE16583: Genomic landscape of meningiomas: genotyping Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-16584 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiles of meningiomas
Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, usually benign and frequently associated with neurofibromatosis type 2. Here we define a human meningioma-typical miRNA profile and characterize effects of one down-regulated mi...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-17792 | biostudies-arrayexpress
TranscriptomicsGenomic landscape of meningiomas: genotyping
Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed global genetic and genomic analysis of 85 meni...
ORGANISM(S): Homo sapiens 
2011-10-11 | E-GEOD-16583 | biostudies-arrayexpress
TranscriptomicsGenomic landscape of meningiomas: gene expression
Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed global genetic and genomic analysis of 85 meni...
ORGANISM(S): Homo sapiens 
2010-11-30 | E-GEOD-16581 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.
We report genomic analysis of 300 meningiomas, the most common primary brain tumors, leading to the discovery of mutations in TRAF7, a proapoptotic E3 ubiquitin ligase, in nearly one-fourth of all meningiomas. Mutations in TRAF7 commonly occurred with a recurrent mutation (K409Q) in KLF4, a transcri...
ORGANISM(S): Homo sapiens 
2014-05-29 | E-GEOD-58037 | biostudies-arrayexpress
TranscriptomicsGeneChip Mapping 500K set and Genome-Wide Human SNP 6.0 Array in meningioma tumors
Cytogenetic profiles of 50 meningiomas using high-density GeneChip Mapping 500K set and Genome-Wide Human SNP 6.0 Array in the tumor tissues and in the peripheral blood of the same patients. A total of two hundred 500k arrays (100 tumor samples and 100 blood samples) and 14 SNP6.0 arrays (7 tumour ...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-42624 | biostudies-arrayexpress
GenomicsGenomic Characterization of Meningiomas

Meningiomas are the most common primary brain tumor in the US. Although the tumor suppressor gene NF2 is disrupted in approximately half of meningiomas, the complete spectrum of genetic changes in meningiomas remains poorly understood, particularly in the large subset of tumors without NF2 altera...

phs000552.v1.p1 | EGA
ProteomicsProteomics data of WHO I and WHO III meningiomas
Proteomics data of endothelial meningiomas, fibrous meningiomas and anaplastic meningiomas
ORGANISM(S): Homo Sapiens 
2022-03-17 | PXD032342 |
TranscriptomicsMeningiomas tumor recurrence and metabolic aggressiveness expression profile
The aim of this study was to determine the relationship between gene expression profiles and new metabolic subgroups of benign meningioma with potential clinical relevance. 19 human meningiomas biopsies were obtained at the Department of Neurosurgery of the Clinical University Hospital of Valencia. ...
ORGANISM(S): Homo sapiens 
2012-08-31 | E-MEXP-3586 | biostudies-arrayexpress
ProteomicsProteomic analysis of meningiomas reveals clinically-distinct molecular patterns
Meningiomas represent one of the most common and clinically heterogeneous brain tumor types that only modestly correlate with histopathologic features. While emerging molecular profiling efforts have linked specific genomic drivers to distinct clinical patterns, the proteomic landscape of meningioma...
ORGANISM(S): Homo sapiens (Human) 
2019-05-30 | PXD012923 | Pride
Meningiomas Neuro-oncology Mass spectrometry Stratification Proteome 
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