Sort   by:  
 Page size 
TranscriptomicsPredicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1
Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To th...
ORGANISM(S): Homo sapiens 
2018-10-04 | E-MTAB-7210 | biostudies-arrayexpress
TranscriptomicsA mesenchymal stromal cell gene signature for donor age
Human aging is associated with loss of function and regenerative capacity. Human bone marrow derived mesenchymal stromal cells (hMSCs) are involved in tissue regeneration, evidenced by their capacity to differentiate into several lineages and therefore are considered the gold standard for cell-based...
ORGANISM(S): Homo sapiens 
2012-07-20 | E-GEOD-39540 | biostudies-arrayexpress
TranscriptomicsH3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells [twins]
In differentiated cells, aging is associated with hypermethylation of DNA regions enriched in repressive histone posttranslational modifications. However, the chromatin marks associated with changes in DNA methylation in adult stem cells during lifetime are still largely unknown. Here, DNA methylati...
ORGANISM(S): Homo sapiens 
2014-09-25 | E-GEOD-52113 | biostudies-arrayexpress
TranscriptomicsH3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells [MSCs]
In differentiated cells, aging is associated with hypermethylation of DNA regions enriched in repressive histone posttranslational modifications. However, the chromatin marks associated with changes in DNA methylation in adult stem cells during lifetime are still largely unknown. Here, DNA methylati...
ORGANISM(S): Homo sapiens 
2014-09-25 | E-GEOD-52112 | biostudies-arrayexpress
Sort   by:  
 Page size