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TranscriptomicsMesendoderm induction
ES cells are differentiated into mesenderm cell linage by Activin A treatment. During this differentaition, gene expression profile of ES cells, day 4 mesendoderm cell, day 5 mesendoderm cells and mesoderm cells are examined.
ORGANISM(S): Mus musculus 
2009-06-12 | E-MEXP-1672 | biostudies-arrayexpress
TranscriptomicsIdentification of mesendoderm precursor- and neurectoderm precursor-enriched genes in Zebrafish embryos
We have developed a method for rapidly identifying early, regionally-expressed molecules: FACS-Assisted Microdissection of Photolabeled cells (FAM-P). For our first FAM-P project, we injected embryos with purified Kaede protein, a stony coral protein that fluoresces at 514 nm (green) prior to- and 5...
ORGANISM(S): Danio rerio 
2010-05-26 | E-GEOD-8654 | biostudies-arrayexpress
ProteomicsHuman organoids uncover PTEN-driven mesendoderm specification via inhibition of retinoic acid signaling pathways
Epiblast cells ingress into the primitive streak, undergoing mesendoderm (MES) specification, which subsequently gives rise to the mesoderm and endoderm. Although recent advances in human organoid technology facilitating the study of early post-implantation development, robust human models that accu...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD065688 | Pride
Mesendoderm Pten Retinoic acid 
TranscriptomicsChIP-seq of FOXK2 in human embryonic stem cells H1 ESC, and the differentiated mesendoderm cells and and NPC cells
In order to investigate the genome-wide binding profile of the forkhead transcription factor FOXK2 in human embryonic stem cells (ESCs) and downstream cell types, we generated the ChIP-seq data of FOXK2 in H1 ESC cells and two differentiated types of cells, mesendoderm cells and NPC cells.
ORGANISM(S): Homo sapiens 
2020-12-21 | E-MTAB-9630 | biostudies-arrayexpress
Genomicsmesendoderm differentiation with Hif-1a knockdown
mesendoderm differentiation with Hif-1a knockdown
PRJNA826451 | ENA
UnknownPHD2 safeguards modest mesendoderm development.
Not available
S-EPMC11380689 | biostudies-literature
UnknownA transcribed enhancer dictates mesendoderm specification in pluripotency.
Not available
S-EPMC5703900 | biostudies-literature
GenomicsChanging the Waddington landscape to control mesendoderm competence -- RNA-seq
Changing the Waddington landscape to control mesendoderm competence -- RNA-seq
PRJNA626448 | ENA
GenomicsChanging the Waddington landscape to control mesendoderm competence -- ATAC-seq
Changing the Waddington landscape to control mesendoderm competence -- ATAC-seq
PRJNA627245 | ENA
TranscriptomicsA novel role for ASCL1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT function
Maternally expressed proteins function in vertebrates to establish the major body axes of the embryo, and to establish a pre-pattern that sets the stage for later acting zygotic signals. This pre-pattern drives the propensity of Xenopus animal cap cells to adopt neural fates under various experiment...
ORGANISM(S): Xenopus laevis 
2016-01-16 | E-GEOD-76915 | biostudies-arrayexpress
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