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ProteomicsIncrease in harmful R-loops associates with different alterations in mRNP composition
Understanding how the assembly of nascent mRNA into a ribonucleoprotein (mRNP) influences R-loop homeostasis is crucial for gaining insights into the cellular mechanisms that prevent genome instability. Here, we identify three RNA-binding proteins, Rie1, Rim4 and She2, whose stoichiometry is importa...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-06-13 | PXD057248 | Pride
R-loops Tho complex Rna-binding proteins Messenger ribonucleoparticle 
UnknownEpstein-Barr Virus Protein EB2 Stimulates Translation Initiation of mRNAs through Direct Interactions with both Poly(A)-Binding Protein and Eukaryotic Initiation Factor 4G.
Not available
S-EPMC5774873 | biostudies-literature
TranscriptomicsIntegrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (RNA-Seq)
Understanding how RNA binding proteins control the splicing code is fundamental to human biology and disease. Here we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alterna...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-34995 | biostudies-arrayexpress
TranscriptomicsIntegrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (CLIP-Seq)
Understanding how RNA binding proteins control the splicing code is fundamental to human biology and disease. Here we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alterna...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-34993 | biostudies-arrayexpress
TranscriptomicsIntegrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (splicing arrays)
Understanding how RNA binding proteins control the splicing code is fundamental to human biology and disease. Here we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alterna...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-34992 | biostudies-arrayexpress
TranscriptomicsTma108, a putative M1 aminopeptidase, is involved in ribosome specialization in Saccharomyces cerevisiae
We performed subcellular fractionation of the polysomes associated with the mitochondrial surface (mitopolysomes) in wild type or Tma108 deleted yeast strains and measured the mRNA enrichment in these fractions by competitive hybridization on microarrays against the corresponding total RNAs. This wa...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-24 | E-MTAB-3922 | biostudies-arrayexpress
TranscriptomicsIntegrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins
This SuperSeries is composed of the following subset Series: GSE34992: Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (splice array) GSE34993: Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP p...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-34996 | biostudies-arrayexpress
TranscriptomicsTma108, a putative M1 aminopeptidase, is involved in ribosome specialization in Saccharomyces cerevisiae
We performed RIP (RNA-IP experiments) in the yeast Saccharomyces cerevisiae, immunoprecipitating either Tma108, Scp160, Tma46 or Rpl16. The RNAs present in the IPs were analyzed by microarray competitive hybridization against total RNAs (Input). Our goal was to identify the RNAs which are targeted,...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-24 | E-MTAB-3881 | biostudies-arrayexpress
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