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MetabolomicsNPM-ALK metabolic regulation
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ORGANISM(S): Homo sapiens 
ST000016 | MetabolomicsWorkbench
MetabolomicsUnique metabolic regulation of micromeres contributes to their inductive signaling in the sea urchin embryo

In many multicellular organisms, a group of cells called organizers plays critical roles by sending signals to adjacent cells and controlling patterning events such as embryogenesis and tissue morphogenesis. Recent studies suggest that these organizers or inductive cells facilitate the downstream...

2025-07-07 | MTBLS5017 | MetaboLights
MetabolomicsPhotosynthetic Carbon Partitioning and Metabolic Regulation in Response to Very-Low and High CO2 in Microchloropsis gaditana NIES 2587
Photosynthetic organisms fix inorganic carbon through carbon capture machinery (CCM) that regulates the assimilation and accumulation of carbon around ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco). However, few constraints that govern the central carbon metabolism are regulated by the ca...
2022-01-14 | MTBLS1778 | MetaboLights
MetabolomicsHUMSCs repair CCl4-induced chronic liver injury in rats via metabolic regulation

To explore the effect of human umbilical cord mesenchymal stem cells (HUMSCs) on repairing CCl4-induced chronic liver injury in rats by intravenous injection and analyze the promising metabolites.

2026-02-03 | MTBLS13826 | MetaboLights
MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
MetabolomicsMicroRNA-mediated regulation of lipid metabolism in virus-infected Emiliania huxleyi.
The interactions between Emiliania huxleyi and E. huxleyi virus (EhV) regulate marine carbon and sulfur biogeochemical cycles and play a prominent role in global climate change. As a large DNA virus, EhV has developed a novel 'virocell metabolism' model to meet its high metabolic needs. Although it ...
2024-01-16 | MTBLS5178 | MetaboLights
MetabolomicsSynergistic regulation of Codonopsis pilosula growth and metabolism by Trichoderma, salicylic acid and methyl jasmonate
Endophytic fungi can mediate salicylic acid (SA)- and methyl jasmonate (MeJA)-related signaling in medicinal plants, thereby influencing metabolite synthesis, stress resistance, and growth development. Experimental groups comprised control, Trichoderma longibrachiatum inoculation (FG), FG+SA (FS), F...
2026-04-16 | MTBLS14293 | MetaboLights
MetabolomicsSynergistic regulation of Codonopsis pilosula growth and metabolism by Trichoderma, salicylic acid and methyl jasmonate
Endophytic fungi can mediate salicylic acid (SA)- and methyl jasmonate (MeJA)-related signaling in medicinal plants, thereby influencing metabolite synthesis, stress resistance, and growth development. Experimental groups comprised control, Trichoderma longibrachiatum inoculation (FG), FG+SA (FS), F...
2026-04-22 | MTBLS14304 | MetaboLights
MetabolomicsMulti-omics insights into high-carotenoid hybrid potato lines: enhanced nutritional quality and metabolic regulation for food applications

Modern potato varieties often exhibit low carotenoid content, limiting their nutritional value and processing performance. This study employed a multi-omics approach (physicochemical analysis, metabolomics, mineral profiling, transcriptomics, and microbiome sequencing) to investigate the molecula...

2025-11-12 | MTBLS13298 | MetaboLights
MetabolomicsMycobacterium tuberculosis VadK required for regulation of the methylcitrate cycle and virulence

The evolution of new enzymatic functions is constrained and guided by the architecture of an organism’s metabolic and regulatory networks and environmental constraints. Here, we identify a kinase that has evolved from pyruvate phosphate dikinase. Through biochemical and systems-lev...

2026-04-21 | MTBLS13906 | MetaboLights
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