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MetabolomicsMolecular mechanisms of growth differences in large yellow croaker: Metabolomic and metagenomic analyses

Gut microbiota can modulate nutrient metabolism, considerably affecting host growth and development. However, mechanisms by which gut microbiota regulate large yellow croaker (LYC; Larimichthys crocea) growth remain unclear. We assessed gut contents of fast-growing male (IWHM) and female (IWHF) L...

2024-08-02 | MTBLS10000 | MetaboLights
MetabolomicsAppropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
16S metagenomic analysis has provided much information about the intestinal microbiome. However, there are no reports that describe their appropriate taxonomic classification rank. Moreover, studies differ on the taxonomic ranking of the same microorganism. Intestinal microbiome exerts a significant...
2017-02-20 | MTBLS376 | MetaboLights
MetabolomicsSpirulina Alleviates Functional Constipation by Remodeling Gut Microbiota and Fecal Metabolites: A Metagenomic and Metabolomic Study
Abstract Objective: Functional constipation (FC) is a common gastrointestinal disorder that significantly affects quality of life. Increasing evidence suggests that gut microbiota and their derived metabolites play a critical role in FC, yet the therapeutic potential of Spirulina and its underlying ...
2026-09-30 | MTBLS15871 | MetaboLights
MetabolomicsColorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles
Not available
ORGANISM(S): Homo sapiens 
ST001307 | MetabolomicsWorkbench
MetabolomicsPessary Therapy Restores Vaginal Microbiome Homeostasis in Severe Pelvic Organ Prolapse: A Longitudinal Metagenomic and Metabolic Analysis
Pelvic organ prolapse (POP), affecting up to 50% of elderly women, disrupts vaginal microbial homeostasis, yet the impact of first-line pessary therapy on microbiome dynamics remains poorly characterized. This prospective cohort study employed metagenomic sequencing and clinical metrics to longitudi...
2025-07-16 | MTBLS12722 | MetaboLights
MetabolomicsMetagenomic and Metabolomic Analysis of Gut Microbiota's Impact on Sperm Motility in Rongchang Boars


This study focused on the association between gut microbiota and sperm motility, with an emphasis on analyzing differential metabolites in the intestines and blood of Rongchang boars from the high sperm motility group (group H) and low sperm motility group (group L). The results reveal...

2025-07-14 | MTBLS12712 | MetaboLights
MetabolomicsMetabolomic and metagenomic insights into WFBG-mediated regulation of gut microbiota and metabolism in broilers

The steady state of gut microbiota is a key factor in regulating the growth of broilers. The regulatory role of wet-fermented brewer's grains (WFBG) in broiler gut development and microbiota is still elusive. In this study, non-targeted metabolomics and 16S rRNA sequencing analysis were used to i...

2025-12-06 | MTBLS13352 | MetaboLights
MetabolomicsIntegrated metagenomic and metabolomic analyses of the effects of total flavonoids of Rhizoma Drynariae on reducing ovariectomized-induced osteoporosis by regulating gut microbiota and related metabolites.

TFRD has been widely used in China to treat osteoporosis (OP). However, the specific molecular mechanism of TFRD against OP has not been fully clarified. Our previous studies have also proved that TFRD could attenuate OP and the clinical equivalent dose of 67.5 mg/kg/d is the effective dose for T...

2025-05-12 | MTBLS11866 | MetaboLights
MetabolomicsMetagenomic and metabolomic analyses reveal the role of gut microbiome-associated metabolites in the muscle elasticity of large yellow croaker (Larimichthys crocea)

The large yellow croaker (LYC, Larimichthys crocea) is highly regarded for its delicious taste and unique flavor. The gut microbiota has the ability to affect the host muscle performance and elasticity by regulating nutrient metabolism. However, the mechanism by which the intestinal micr...

2025-07-31 | MTBLS10457 | MetaboLights
MetabolomicsMulberry Cultivation for Saline-Alkali Land Amelioration: Metagenomic and Metabolomic Perspectives on Soil Biogeochemistry and Leaf Metabolic Profiling
We conducted field trials combined with metabolomic sequencing to evaluate the saline-alkali soil remediation efficiency of mulberry trees, as well as the metabolic responses of mulberry leaves under saline-alkali stress.
2026-08-06 | MTBLS15262 | MetaboLights
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