Methicillin-resistant s. aureus

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Unknown (3718)
Genomics (227)
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Organisms

Staphylococcus aureus (99)
Mus musculus (13)
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Staphylococcus aureus subsp. aureus MW2 (5)
Coxiella burnetii (5)
Staphylococcus aureus subsp. aureus MRSA252 (4)
Staphylococcus aureus subsp. aureus USA300 (4)
Staphylococcus haemolyticus JCSC1435 (4)
Chlamydia trachomatis D/UW-3/CX (4)
Chlamydia caviae GPIC (4)
Chlamydia muridarum (4)
Rickettsia rickettsii (4)
Staphylococcus epidermidis ATCC 12228 (4)
Granulibacter bethesdensis (4)
Coxiella burnetii RSA 493 (4)
Chlamydia pneumoniae AR39 (4)
Staphylococcus epidermidis RP62A (4)
Borreliella burgdorferi B31 (4)
Staphylococcus aureus subsp. aureus Mu50 (3)
Staphylococcus aureus subsp. aureus USA300_FPR3757 (2)
Staphylococcus aureus subsp. aureus str. Newman (2)
Mycobacterium tuberculosis (2)
Staphylococcus aureus subsp. aureus N315 (2)
Staphylococcus aureus subsp. aureus COL (2)
Staphylococcus aureus subsp. aureus NCTC 8325 (2)
Anopheles gambiae (1)
Enterococcus faecalis (1)
Mammaliicoccus sciuri (1)
Staphylococcus aureus USA300-0114 (1)
Staphylococcus aureus subsp. aureus MSSA476 (1)

Organisms

Staphylococcus aureus (76)
Homo sapiens (7)
Staphylococcus aureus subsp. aureus COL (5)
Mus musculus (5)
Staphylococcus aureus subsp. aureus MRSA252 (2)
Staphylococcus aureus USA300-0114 (1)
Staphylococcus aureus subsp. aureus MW2 (1)
Staphylococcus phage ESa2 (1)
Staphylococcus aureus subsp. aureus USA300_FPR3757 (1)
Staphylococcus aureus subsp. aureus PB32 (1)
Staphylococcus aureus CA-347 (1)
Staphylococcus aureus subsp. aureus USA300_TCH1516 (1)
Staphylococcus aureus subsp. aureus USA300 (1)
Staphylococcus aureus subsp. aureus str. Newman (1)
Mammaliicoccus sciuri (1)
46170 (1)
Staphylococcus pseudintermedius (1)
Streptomyces (1)
Staphylococcus (1)
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human oral metagenome (1)
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Tissue

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Disease

Disease free (2)
Wounds and Injuries (2)
Plasmodium berghei CTRP knockout strain (Dessens et al., 1999) infection (1)
Not Available (1)
Commensal bacterial infectious disease (1)
Osteomyelitis (1)

Technology Type

Mass Spectrometry (42)
Shotgun proteomics (26)
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Mass spectrometry (7)
Mass spectrometry assay (4)
Affinity purification coupled with mass spectrometry proteomics (3)
Data-dependent acquisition (2)
Data-independent acquisition (2)
Gel-based experiment (2)
SWATH MS (2)
DiaPASEF (1)
Top-down proteomics (1)

Instrument Platform

Agilent GC 7890A coupled with a single quadrupole MSD 5975C (5)
LTQ Velos ETD (5)
Liquid Chromatography MS - positive - reverse phase (4)
Liquid Chromatography MS - negative - reverse phase (4)
Spectronic Helios Alpha UV-Vis spectrophotometer (3)
Liquid Chromatography MS - positive - reverse-phase (3)
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Sequel (1)
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Instrument (1)
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Q Exactive (1)
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Publication Date

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2020 (8)
2015 (6)
2014 (6)
2007 (5)
2018 (4)
2017 (4)
2008 (4)
2005 (1)

CHEBI ID

CHEBI:17497 (2)
CHEBI:30769 (2)
CHEBI:170071 (1)
CHEBI:170070 (1)
CHEBI:170061 (1)
CHEBI:172382 (1)
CHEBI:172381 (1)
CHEBI:170058 (1)
CHEBI:170054 (1)
CHEBI:170051 (1)
CHEBI:170047 (1)
CHEBI:170046 (1)
CHEBI:170043 (1)
CHEBI:170042 (1)
CHEBI:170040 (1)
CHEBI:170039 (1)
CHEBI:170037 (1)
CHEBI:170033 (1)
CHEBI:170031 (1)
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CHEBI:170024 (1)
CHEBI:170020 (1)
CHEBI:170018 (1)
CHEBI:170044 (1)
CHEBI:170022 (1)
CHEBI:170014 (1)
CHEBI:143106 (1)
CHEBI:170052 (1)

Metabolite Name

Hypoxanthine (5)
Kynurenic acid (4)
Phytosphingosine (4)
Choline (4)
4-Hydroxybenzaldehyde (4)
Oleamide (4)
Adenosine (4)
Uric acid (4)
L-Tyrosine (4)
Ranolazine (3)
Phenol (3)
2-Hydroxy-2-methylbutyric acid (3)
Uracil (3)
Betaine (3)
Thymine (3)
7-Methylguanine (3)
Undecanedioic acid (3)
Methionine (3)
Phenylpyruvic acid (3)
Monobutyl phthalate (3)
Sebacic acid (3)
Urocanic acid (3)
Spermidine (3)
Guanine (3)
Cytosine (3)
2-Hydroxycinnamic acid (3)
Salicylic acid (3)
Riboflavin (3)
Mevalonic acid (3)
L-Serine (3)

First Public Date

2024 (34)
2014 (30)
2025 (23)
2026 (21)
2022 (18)
2023 (14)
2021 (14)
2020 (14)
2013 (13)
2019 (10)
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Modelling Approach

Constraint-based model (3)
Computational model (2)

Lab affiliation

Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (2)
Chemical and Biological Engineering, The Hong Kong University of Science and Technology (HKUST) (2)
Department of Pharmaceutics, School of Pharmaceutical Sciences of Wenzhou Medical University (2)
1 College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates 2 School of Dentistry, Cardiff University, Cardiff, United Kingdom (1)
Assoc. Prof. Dr. Christian S. Lentz Associate Professor, Department of Medical Biology, UiT- The Arctic University of Norway, 9019 Tromsø, Norway (1)
Biological Mass Spectrometry Lab,Department of Translational Medicine (DiMeT),Center for Translational Research on Autoimmune & Allergic Diseases - CAAD,University of Piemonte Orientale, Corso Trieste 15/A, 28100, Novara, Italy (1)
Biomedical Science Research Complex (1)
Center for Integrated Protein Science at the Department of Chemistry, Technische Universität München, Garching b. München 85747, Germany; Chair of Organic Chemistry II, Technische Universität München, Garching b. München 85747, Germany (1)
Centre for Bioinnovation, University of the Sunshine Coast (1)
Centre for Synthetic and Systems Biology (SynthSys) University of Edinburgh Max Born Crescent CH Waddington Building, room 3.06 EH9 3BF Edinburgh (1)
Chemical and Biological Engineering Department, The Hong Kong University of Science and Technology (HKUST) (1)
College of Animal Science, Jilin University, China (1)
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Science (1)
Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University (1)
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA Arkansas Children's Research Institute, 13 Children's Way, Little Rock, AR 72205, USA (1)
Department of Biomedical Sciences, University of Sassari, Sassari, 07100, Italy (1)
Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology (HKUST) (1)
Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology (1)
Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, DK-9220, Aalborg East, Denmark (1)
Department of Chemistry, The University of Hong Kong (1)
Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 75123, Uppsala, Sweden (1)
Department of Medical Biology, UiT- The Arctic University of Norway, 9019 Tromsø, Norway (1)
Department of Plant Pathology, Entomology, and Microbiology Iowa State University (1)
Freie Universität Berlin, Institute for Biology-Microbiology, Königin-Luise-Strasse 12-16, D-14195 Berlin, Germany. (1)
Genecology Research Centre, University of the Sunshine Coast (1)
Institute of Microbiology, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany (1)
Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, System Biology Laboratory (1)
MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China (1)
Microbiology (1)
Molecular and Cellular Biology Department, University of Guelph, 50 Stone Rd. E., Guelph, ON, N1H 2W1 (1)

IsPrivate

False (5)

Submitter Keywords

Ersilia (2)
FAIR-AIML (2)
Machine Learning Model (2)
Not Peer Reviewed (1)

Classification

bacteria (92)
viruses (1)

Modification

Not available (2)

Study type

Transcription profiling by array (49)
RNA-seq of coding RNA (12)
Comparative genomic hybridization by array (6)
Unknown experiment type (2)
DNA-seq (1)
Proteomic profiling by array (1)

Release Date

2022 (415)
2021 (401)
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2019 (248)
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2017 (175)
2016 (174)
2015 (149)
2014 (114)
2013 (102)
2012 (91)
2011 (67)
2010 (64)
2026 (48)
2009 (43)
2008 (30)
2007 (25)
2006 (24)
2005 (16)
2004 (12)
2000 (8)
2001 (7)
2003 (6)
2002 (6)
1999 (6)
1998 (4)

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Valine potentiates cefoperazone-sulbactam to kill methicillin resistant Staphylococcus aureus

Metabolic state-reprogramming approach was extended from Gram-negative bacteria to Gram-positive bacterium methicillin-resistant Staphylococcus aureus (MRSA) for identifying desired reprogramming metabolites to synergize existing antibiotic killing to MRSA. Metabolomics comparison between MRSA an...

2024-12-12 | MTBLS11540 | MetaboLights

Computational Ranking of Yerba Mate Small Molecules Based on Their Predicted Contribution to Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus

The aqueous extract of yerba mate, a South American tea beverage made from Ilex paraguariensis leaves, has demonstrated bactericidal and inhibitory activity against bacterial pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). The gas chromatography-mass spectrometry (GC-MS) ana...

2015-03-19 | MTBLS170 | MetaboLights

Discovery of isokurarinone as an ATCase-Engaging Lead with potent activity against methicillin-resistant Staphylococcus aureus

The global proliferation of methicillin-resistant Staphylococcus aureus (MRSA) persists as a significant contributor to challenging infections, highlighting the urgent necessity for therapies that utilize novel mechanisms. Aspartate transcarbamoylase (ATCase), which catalyzes the initial committe...

2026-01-14 | MTBLS13673 | MetaboLights

The killing mechanism of teixobactin against methicillin-resistant Staphylococcus aureus (MRSA): An untargeted metabolomics study

The discovery of antibiotics has led to the effective treatment of bacterial infections that were otherwise fatal and has had a transformative effect on modern medicine. Teixobactin is an unusual depsipeptide natural product that was recently discovered from a previously unculturable soil bacteri...

2020-04-30 | MTBLS1569 | MetaboLights

Exercise-driven gut microbiota alterations enhance colonization resistance against methicillin-resistant Staphylococcus aureus

Gut microbiota plays a crucial role in resisting the invasion of pathogens, particularly multidrug-resistant (MDR) bacteria, which pose a significant threat to public health. While exercise offers numerous health benefits, its impact on host colonization resistance remains largely unclear. In thi...

2025-02-19 | MTBLS12219 | MetaboLights

StaphVar-DNA microarray analysis of accessory genome of community-acquired methicillin resistant Staphylococcus aureus

Approximatively 75% of the genome of S. aureus (“core” genome) are highly conserved between strains, whereas the remaining 25% (“accessory” genome) are composed of variable regions that are mostly composed of mobile genetic elements (MGE), containing virulence and resistance genes. We have developed...

ORGANISM(S): Staphylococcus aureus

2009-02-14 | E-GEOD-13702 | biostudies-arrayexpress

Response of Methicillin-resistant Staphylococcus aureus to Amicoumacin A

Methicillin resistant Staphylococcus aureus (MRSA) infection is becoming refractory to existing antibiotic therapy owing to the inherent ability of S. aureus to develop rapid resistance and is considered a major threat to public health. We found that a natural isolate of Bacillus pumilus from the C...

ORGANISM(S): Staphylococcus aureus

2012-07-30 | E-GEOD-31342 | biostudies-arrayexpress

Detection of mobile-genetic-element variation between colonizing and infecting hospital-associated methicillin-resistant Staphylococcus aureus isolates.

Whole-genome analysis by 62-strain microarray showed variation in resistance and virulence genes on mobile genetic elements (MGEs) between 40 isolates of methicillin-resistant Staphylococcus aureus (MRSA) strain CC22-SCCmecIV but also showed (i) detection of two previously unrecognized MRSA transmis...

ORGANISM(S): Staphylococcus aureus

2012-10-29 | E-BUGS-128 | biostudies-arrayexpress

Response of methicillin-resistant Staphylococcus aureus USA300 to a subinhibitory concentration of thioridazine - alone and in combination with dicloxacillin

Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant S. aureus (MRSA) by Î²-lactam antibiotics, however, the mechanism underlying the synergy between TDZ and Î²-lactams is not fully understood. In the present study we ...

ORGANISM(S): Staphylococcus aureus subsp. aureus USA300_FPR3757

2013-05-20 | E-GEOD-43759 | biostudies-arrayexpress

Transcription profiling of S. aureus to investigate an outbreak of severe infections with community-acquired methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin following immunization - duplicate of E-BUGS-45

BACKGROUND: Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination. METHODS AND FINDINGS: We carried out a field investigation after adve...

ORGANISM(S): Staphylococcus aureus

2009-01-16 | E-BUGS-45 | biostudies-arrayexpress

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