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Lysosomes are a major site of intracellular acidic hydrolase-mediated proteolysis and cellular degradation. The export of low-molecular catabolic end products from the lysosomal lumen to the cytosol is facilitated by polytopic transmembrane proteins which mediate secondary active or passive transpor...
ORGANISM(S): Mus musculus (Mouse) 
2019-10-28 | PXD014241 | Pride
In this study, we detected three alleles that caused lymphopenia, splenomegaly, progressive liver pathology and extramedullary hematopoiesis (EMH), resulting from N-ethyl-N-nitrosourea (ENU)-induced mutations in the major facilitator superfamily domain containing 1 protein (Mfsd1) which encodes a ly...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092540 | MassIVE
In this study, we detected three alleles that caused lymphopenia, splenomegaly, progressive liver pathology and extramedullary hematopoiesis (EMH), resulting from N-ethyl-N-nitrosourea (ENU)-induced mutations in the major facilitator superfamily domain containing 1 protein (Mfsd1) which encodes a ly...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092538 | MassIVE
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