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UnknownImmune responses to oligomeric α-synuclein in Parkinson's disease peripheral blood mononuclear cells.
Not available
S-EPMC11377674 | biostudies-literature
GenomicsTRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
DNA lesions encountered by replicative polymerases threaten genome stability and cell cycle progression. Here we report the identification of mutations in TRAIP, encoding an E3 RING ubiquitin ligase, in patients with microcephalic primordial dwarfism/Seckel syndrome. We establish that TRAIP relocali...
EGAS00001001501 | EGA
UnknownLocal Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein.
Not available
S-EPMC12023029 | biostudies-literature
GenomicsWhole Genome Sequencing of MCF10A cells
The non-tumourigenic human breast epithelial cell line MCF10A is the cell line most commonly used as a model for normal human breast cells. This dataset provides a reference genome for MCF10A. The whole genome, high-throughput sequencing was performed using the Illumina NovaSeq 6000 PE150 system. Bo...
ORGANISM(S): Homo sapiens 
2023-10-01 | E-MTAB-13191 | biostudies-arrayexpress
UnknownAssessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy.
Not available
S-EPMC4104112 | biostudies-literature
UnknownTrends in the use and cost of antipsychotics among older adults from 2007 to 2013: a repeated cross-sectional study.
Not available
S-EPMC4933600 | biostudies-literature
TranscriptomicsTranscription profiling of human blood lymphoblasts purified at three time points from childhood ALL samples (0h, 6-8h, 24h after treatment with prednisolone
Glucocorticoids (GC) are in most chemotherapy protocols for lymphoid malignancies, particularly childhood acute lymphoblastic leukaemia (ALL) for their ability to induce apoptosis in malignant blast. The underlying mechanism, however, has so far only been investigated in model systems. This study co...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2842 | biostudies-arrayexpress
TranscriptomicsIdentification and Expression Patterns of Novel Long Non-Coding RNAs in Neural Progenitors of the Developing Mammalian Cortex
Long non-coding (lnc)RNAs play key roles in many biological processes. Elucidating the function of lncRNAs in cell type specification during organ development requires knowledge about their expression in individual progenitor types rather than in whole tissues. To achieve this during cortical develo...
ORGANISM(S): Mus musculus 
2015-04-23 | E-GEOD-65487 | biostudies-arrayexpress
UnknownIdentification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates.
Not available
S-EPMC7220339 | biostudies-literature
ProteomicsArginine methylation, Cob1 - Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl
Arginine methylation, Cob1. Wenya Hou et al Jena University Hospital
ORGANISM(S): Mus musculus (Mouse) 
2018-04-30 | PXD008504 | Pride
Lc-msms 
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