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ProteomicsHuman mitochondrial protein import proteomics - Proteinase K control
Most mitochondrial proteins are encoded in the nucleus and require mitochondrial import after translation in the cytosol. A number of mutations in the mitochondrial protein import machinery have been shown to lead to human pathologies. However, a lack suitable tools to measure mitochondrial protein ...
ORGANISM(S): Homo sapiens (Human) 
2021-12-20 | PXD024066 | Pride
Meprod Tmd Tmt Mitochondrial protein import Human Dda 
ProteomicsPAM complex sequesters from TIM translocon and becomes part of an insoluble protein fraction under protein folding stress
Upon mitochondrial dysfunction, mitophagy has been described to be activated by a breakdown of membrane potential leading to PINK1 accumulation on the outer membrane and engulfment of mitochondria for degradation. However, recent findings have indicated that mitophagy may also be triggered in the ab...
ORGANISM(S): Homo sapiens (Human) 
2022-09-03 | PXD022524 | Pride
Human Mitophagy Hela cell line Pam complex Lc-ms/ms 
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