Sort   by:  
 Page size 
ProteomicsProteome analysis of HepG2 WT and mitochondrial apolipoprotein MIC26 knockout cells under normo- and hyperglycemic conditions
Increased amounts of the mitochondrial apolipoprotein O /MIC26 were found in diabetic patients along with lipid accumulation in murine liver upon MIC26 expression. MIC26 is a MICOS complex constituent present in the mitochondrial inner membrane. Here, we employed a proteomics analysis approach in W...
ORGANISM(S): Homo sapiens (Human) 
2024-09-13 | PXD047246 | Pride
Apolipoproteins Mic26 Mitochondria Micos complex and fatty acid metabolism 
UnknownLiver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism.
Not available
S-EPMC10528355 | biostudies-literature
UnknownMic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Not available
S-EPMC10762189 | biostudies-literature
ProteomicsDNA damage response signaling to mitochondria drives senescence
Cellular senescence is a stress-induced permanent cell cycle arrest typically accompanied by expression of the cyclin-dependent kinase inhibitor p16. Recent studies have suggested that p16-expressing senescent cells accumulate in the body with age and play a causative role in aging. Various stresses...
ORGANISM(S): Homo sapiens (Human) 
2025-01-14 | PXD036980 | Pride
Human Lc-ms/ms 
UnknownLifespan Extension of Podospora anserina Mic60-Subcomplex Mutants Depends on Cardiolipin Remodeling.
Not available
S-EPMC9099538 | biostudies-literature
ProteomicsUrolithin A protects hepatocytes from palmitic acid-induced ER stress by regulating calcium homeostasis in the MAM
An ellagitannin-derived metabolite Urolithin A (UA) has emerged as a potential therapeutic agent for metabolic disorders due to its antioxidant, anti-inflammatory, and mitochondrial function-improving properties, but its efficacy in protecting against ER stress remains underexplored. The endoplasmic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-02 | MSV000096011 | MassIVE
Sort   by:  
 Page size