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GenomicsMitochondrial Apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
Mitochondrial Apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
PRJNA1046107 | ENA
TranscriptomicsMitochondrial Apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
A variety of metabolic disorders are aggravated by obesity. Since mitochondria play key roles in various catabolic and anabolic reactions encompassing lipid metabolism, optimal functioning of mitochondria is critical in preventing various pathologies. Increased amounts of the apolipoprotein O /MIC26...
ORGANISM(S): Homo sapiens 
2023-12-01 | GSE248848 | GEO
ProteomicsComplexome profiling of MICOS complex, impact of subunits MIC26 and MIC27
Here we analysed the impact of two subunits (MIC26 and MIC27) on the assembly and stability of the mitochondrial contact site and cristae organizing system (MICOS) complex.
ORGANISM(S): Homo sapiens (Human) 
2020-07-28 | PXD016732 | Pride
Micos Oxidative phosphorylation system Lc-msms Complexome profiling 
ProteomicsComplexome profiling of mitochondrial protein complexes in single and double MIC26 and MIC27 knockout cells
Here we analysed the impact of two subunits of the mitochondrial contact site and cristae organizing system (MICOS) complex, MIC26 and MIC27, on the assembly and stability of mitochondrial complexes of the oxidative phosphorylation system (OXPHOS).
ORGANISM(S): Homo sapiens (Human) 
2020-07-28 | PXD016733 | Pride
Micos Oxidative phosphorylation system Lc-msms Complexome profiling 
ProteomicsProteome analysis of HepG2 WT and mitochondrial apolipoprotein MIC26 knockout cells under normo- and hyperglycemic conditions
Increased amounts of the mitochondrial apolipoprotein O /MIC26 were found in diabetic patients along with lipid accumulation in murine liver upon MIC26 expression. MIC26 is a MICOS complex constituent present in the mitochondrial inner membrane. Here, we employed a proteomics analysis approach in W...
ORGANISM(S): Homo sapiens (Human) 
2024-09-13 | PXD047246 | Pride
Apolipoproteins Mic26 Mitochondria Micos complex and fatty acid metabolism 
UnknownMitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways.
Not available
S-EPMC11472510 | biostudies-literature
UnknownMIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes.
Not available
S-EPMC7425215 | biostudies-literature
UnknownMIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins.
Not available
S-EPMC10243636 | biostudies-literature
UnknownMutation in the MICOS subunit gene <i>APOO</i> (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features.
Not available
S-EPMC7116790 | biostudies-literature
UnknownMyristoyl group-aided protein import into the mitochondrial intermembrane space.
Not available
S-EPMC6362269 | biostudies-literature
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