Sort   by:  
 Page size 
TranscriptomicsFicolin-1 is upregulated in leukocytes and glomeruli from microscopic polyangiitis patients
To search for new markers of active lesions that might help better understand the molecular basis of MPA and aid in its diagnosis, DNA microarray analysis was performed with peripheral blood mononuclear cells (PBMCs). A total of 12 sets of two color arrays were performed and each individual array in...
ORGANISM(S): Homo sapiens 
2013-08-18 | E-GEOD-41744 | biostudies-arrayexpress
MetabolomicsIntegrated transcriptomic and metabolomic analysis reveals insights into drought stress in Plantago lanceolata
Background: The unique vertical climate of Yunnan Province provides diverse resources for livestock development; however, frequent seasonal droughts during winter and spring result in a severe imbalance between forage supply and demand, constituting a major bottleneck for sustainable pastoral agricu...
2026-05-06 | MTBLS14435 | MetaboLights
MetabolomicsDetection of adulteration in Iranian saffron samples by 1H NMR spectroscopy and multivariate data analysis techniques
Introduction: The high market value of saffron (Crocus sativus L.) has made it an attractive candidate for adulteration. Safflower (Carthamus tinctorius L.) and tartrazine are among the most common herbal and synthetic foreign materials that may be added to pure saffron for the purpose of adulterati...
2017-07-20 | MTBLS331 | MetaboLights
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
ProteomicsThe association between baseline serum lipids and renal outcome in microscopic polyangiitis patients
ANCA associated vasculitis(AAV) is a systemic vasculitis of small vessels, characterzied by injury of vascular endothelial cells induced by abnormally activated neutrophils. Microscopic polyangiitis (MPA) is a member of AAV with a high risk of kidney involvement. Blood lipid disorder promotes endoth...
ORGANISM(S): Homo sapiens (Human) 
2025-01-06 | PXD045969 | Pride
Plasma 
TranscriptomicsBiological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols
We compared early biological changes in mice after inhalation exposures to cigarette smoke or e-vapor aerosols (MarkTen® cartridge with Carrier, Test-1, or Test-2 formulations; 4% nicotine). Female C57BL/6 mice were exposed to 3R4F cigarette smoke or e-vapor aerosols by nose-only inhalation for up t...
ORGANISM(S): Mus musculus 
2021-02-28 | E-MTAB-10166 | biostudies-arrayexpress
TranscriptomicsMPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary tumors with different hormonal requirements
Introduction: Over the past several years, we have been interested in understanding the mechanisms by which hormone-dependent (HD) mammary carcinomas grow in the absence of the stimulatory hormone. We have hypothesized that the stromal compartment plays a pivotal role in the acquisition of the hormo...
ORGANISM(S): Mus musculus 
2011-01-22 | E-GEOD-23214 | biostudies-arrayexpress
GenomicsWhole blood transcriptomic analysis of ANCA-associated vasculitis
Whole blood mRNA sequencing from 30 patients with AAV (granulomatosis with polyangiitis/GPA, n=22) and microscopic polyangiitis (MPA, n=8) combined with functional enrichment and network analysis for aberrant pathways. Key genes and pathways were validated in an independent cohort of 18 AAV patients...
EGAS00001006704 | EGA
MetabolomicsAnalysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis
Male and female Plasmodium falciparum gametocytes are the parasite lifecycle stage responsible for transmission of malaria from the human host to the mosquito vector. Not only are gametocytes able to survive in radically different host environments, but they are also precursors for male and female g...
2022-04-05 | MTBLS4137 | MetaboLights
ProteomicsMicroscopic and biochemical monitoring of endosomal trafficking and extracellular vesicle secretion in an endogenous in vivo model
Extracellular vesicle (EV) secretion enables cell-cell communication in multicellular organisms. During development, EV secretion and the specific loading of signaling factors in EVs contributes to organ development and tissue differentiation. Here, we present an in vivo model to study EV secretion ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-14 | PXD027290 | Pride
Exosomes Hemolymph Drosophila Intercellular communication Rab35 Fat body Tsp96f Rab11 
Sort   by:  
 Page size