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DR44 is a Rab11 effector protein that is thought to regulate ciliogenesis by competing with pro-ciliogenesis factors for Rab11 binding. The structure of WDR44 and the molecular mechanism of its interaction with Rab11 is unknown. To explore the interactions between these two proteins multiple WDR44 c...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035741 | Pride
Analysis of the interactions between WDR44 and Rab11 utilizing HDX-MS
ORGANISM(S): Homo sapiens (Human) 
2023-02-22 | PXD032837 | Pride
H/D exchange analysis of the GEF SH3BP5 and its interaction with the GTPase Rab11
ORGANISM(S): Homo sapiens (Human) 
2018-09-18 | PXD010586 | Pride
We want to determine the protein networks that are associated with KIF11 in the presenceor absence of Rab11 in Caco2 cells. We performed immunoprecipitation against KIF11 using an anti-KIF11 antibody in control and Rab11 knockdown Caco2 cells In addition, we included samples of no antibody control t...
ORGANISM(S): Homo sapiens (Human) 
2023-06-05 | PXD042335 | Pride
A siRNA screening using a commercially available membrane trafficking library identified Rab11 as a pro-viral host factor in motor neuron NSC34 cell line infected with EV-A71, a major causative agent of Hand, Foot and Mouth Disease (HFMD). This project aims at deciphering the role of Rab11 during EV...
ORGANISM(S): Homo sapiens (Human) Enterovirus A71 
2024-06-28 | PXD043870 | Pride
Cancer in the intestinal tract is governed by multiple pathways including Wnt, Ras, P53 and Hippo. The GTPase Rab11 regulates endosomal protein trafficking and in a previous report we showed that loss of Rab11 in enterocytes caused intestinal inflammation and hyperplasia in mice and flies. We show h...
ORGANISM(S): Drosophila melanogaster 
2019-12-21 | GSE92705 | GEO
Endocytic recycling controls the return of internalised cargos to the plasma membrane to coordinate their positioning, availability and downstream signalling. The Rab4 and Rab11 small GTPase families regulate distinct recycling routes, broadly classified as fast recycling from early endosomes (Rab4)...
ORGANISM(S): Homo sapiens (Human) 
2023-06-13 | PXD033693 | Pride
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