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UnknownRAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation.
Not available
S-EPMC9615386 | biostudies-literature
UnknownRab4A organizes endosomal domains for sorting cargo to lysosome-related organelles.
Not available
S-EPMC6151265 | biostudies-literature
UnknownKDEL Receptor Trafficking to the Plasma Membrane Is Regulated by ACBD3 and Rab4A-GTP.
Not available
S-EPMC10093020 | biostudies-literature
UnknownIsoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis.
Not available
S-EPMC5658678 | biostudies-literature
UnknownRab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation.
Not available
S-EPMC10960037 | biostudies-literature
ProteomicsProximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Endocytic recycling controls the return of internalised cargos to the plasma membrane to coordinate their positioning, availability and downstream signalling. The Rab4 and Rab11 small GTPase families regulate distinct recycling routes, broadly classified as fast recycling from early endosomes (Rab4)...
ORGANISM(S): Homo sapiens (Human) 
2023-06-13 | PXD033693 | Pride
Bioid Human Rab11a Endocytosis Rab25 Rab4a 
UnknownThe N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin.
Not available
S-EPMC1952073 | biostudies-literature
TranscriptomicsRNA-Sequencing of CD4, CD8 and CD19 splenocytes from mouse models of SLE
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects 20-150 out of 100,000 people globally. Reactive oxygen species (ROS) generation from mitochondrial dysfunction contributes to risk for SLE and autoimmune states and are potential targets for the treatment of autoimmunity. HRES-...
ORGANISM(S): Mus musculus 
2024-02-22 | GSE245413 | GEO
TranscriptomicsTranscription profiling of human CD3-positive T cells from SLE and controls reveals activation of mTOR controls the loss of TCRI? in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation
CD3-positive T cells were negatively isolated from 10 SLE patients and 9 healthy controls without SLE. All of the SLE samples and control samples were compared with one another to identify baseline differences in expression due to the disease. Next, T cell preparations from 4 of the control subjec...
ORGANISM(S): Homo sapiens 
2009-02-28 | E-GEOD-13887 | biostudies-arrayexpress
UnknownWhole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons.
Not available
S-EPMC5605467 | biostudies-literature
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