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ProteomicsDetailing the Structural and Dynamic Interactions Between WDR44 and Rab11
DR44 is a Rab11 effector protein that is thought to regulate ciliogenesis by competing with pro-ciliogenesis factors for Rab11 binding. The structure of WDR44 and the molecular mechanism of its interaction with Rab11 is unknown. To explore the interactions between these two proteins multiple WDR44 c...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035741 | Pride
Hdx-ms Wdr44 Rab11 
ProteomicsDetailing the Structural and Dynamic Interactions Between WDR44 and Rab11
Analysis of the interactions between WDR44 and Rab11 utilizing HDX-MS
ORGANISM(S): Homo sapiens (Human) 
2023-02-22 | PXD032837 | Pride
Hdx-ms Wdr44 Rab11 
UnknownMolecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11.
Not available
S-EPMC9808001 | biostudies-literature
UnknownWDR44 Loss-of-Function Promoter Deletion in a Male Newborn With a Ciliopathy Phenotype.
Not available
S-EPMC11637934 | biostudies-literature
UnknownGRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.
Not available
S-EPMC7199855 | biostudies-literature
UnknownVariants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation.
Not available
S-EPMC10774338 | biostudies-literature
UnknownPhosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.
Not available
S-EPMC6824681 | biostudies-literature
ProteomicsStiffness Programs WDR44 Phosphorylation to Gate Cargo Sorting into Migrasomes
Cells release extracellular vesicles (EVs) for intercellular communication, homeostasis, and microenvironment remodeling, yet how physiological matrix stiffness controls EV cargo sorting remains unclear. Here we show that stiffness programs a cargo-selective sorting pathway in migrasomes, where matr...
ORGANISM(S): Mus Musculus 
PXD083164 |
UnknownAkt Regulates a Rab11-Effector Switch Required for Ciliogenesis.
Not available
S-EPMC7457226 | biostudies-literature
UnknownPathways that affect anterior morphogenesis in C. elegans embryos.
Not available
S-EPMC10168279 | biostudies-literature
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