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MetabolomicsMetabolomics profiling (GC-MS and LC-MS) for time-course differentiation of pre-B cells-like (B3 cell line) under the controlled induction of the transcription factor Ikaros (STATegra Project)
The main goal of the project is to develop a new generation of bioinformatics resources for the integrative analysis of multiple types of 'omics data. These resources include both novel statistical methodologies as well as user-friendly software implementations. STATegra methods address many aspects...
2016-12-15 | MTBLS283 | MetaboLights
ProteomicsNIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1
We found that LC3B is phosphorylated in vitro by STK3, STK4, NEK9, and PKCζ. To identify phosphorylation sites following in vitro phosphorylation, GST-LC3B was overexpressed in E. coli, purified using glutathione-Sepharose 4 Fast Flow beads and incubated in kinase assays with recombinant kinases or ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-23 | PXD016681 | Pride
Microtubule-associated lc3b protein Autophagy In vitro phosphorylation 
GenomicsTranscriptome changes in the retinal pigment epithelial cells of Microtubule-Associated Protein 1 Light Chain 3B gene knockout mouse (LC3b-/-)
Transcriptome changes in the retinal pigment epithelial cells of Microtubule-Associated Protein 1 Light Chain 3B gene knockout mouse (LC3b-/-)
PRJNA935311 | ENA
GenomicsAutophagy driven by a master regulator of hematopoiesis
Developmental and homeostatic remodeling of cellular organelles is mediated by a complex process termed autophagy. The cohort of proteins that constitute the autophagy machinery function in a multistep biochemical pathway. Though components of the autophagy machinery are broadly expressed, autophagy...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-32491 | biostudies-arrayexpress
UnknownSusceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.
Not available
S-EPMC6902724 | biostudies-literature
UnknownMicrotubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.
Not available
S-EPMC6186781 | biostudies-literature
UnknownPeroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).
Not available
S-EPMC6962520 | biostudies-literature
TranscriptomicsTranscriptome changes in the retinal pigment epithelial cells of Microtubule-Associated Protein 1 Light Chain 3B gene knockout mouse (LC3b-/-)
RPE cells from WT and Total RNA was isolated from WT and LC3b-/- mice were isolated by enzymatic treatment and gentle dissociation, followed by RNA extraction. RNA-sequencing by the Next-Generation Sequencing Core of the University of Pennsylvania.
ORGANISM(S): Mus musculus 
2023-05-03 | GSE225344 | GEO
UnknownStructural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy.
Not available
S-EPMC5233613 | biostudies-literature
UnknownAutophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.
Not available
S-EPMC3081281 | biostudies-literature
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