Sort   by:  
 Page size 
TranscriptomicsTranscriptional analysis of multiple brain regions in Parkinson's disease
Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. This SuperSeries is composed of the following subset Series: GSE20168: Transcriptional...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20295 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rats subjected to Roux-en-Y gastruc bypass to characterize of weight loss and weight regain mechanisms
Roux-en-Y gastric bypass (RYGB) is the most effective therapy for morbid obesity, but it has a ~20% failure rate. We used our established RYGB model in diet-induced obese (DIO) Sprague-Dawley rats, which reproduces human bi-phasic body weight (BW) loss pattern, to determine mechanisms contributing t...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-8314 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD3-positive T cells from SLE and controls reveals activation of mTOR controls the loss of TCRI? in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation
CD3-positive T cells were negatively isolated from 10 SLE patients and 9 healthy controls without SLE. All of the SLE samples and control samples were compared with one another to identify baseline differences in expression due to the disease. Next, T cell preparations from 4 of the control subjec...
ORGANISM(S): Homo sapiens 
2009-02-28 | E-GEOD-13887 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of adult zebrafish control and post-lesion retina to investigate the molecular determinants of retinal regeneration in adult vertebrate
Purpose: Investigate the molecular determinants of retinal regeneration in adult vertebrates by analyzing the gene expression profiles of control and post-lesion retina of adult zebrafish, a system that regenerates following injury. Methods: Gene expression profiles of zebrafish retina and brain wer...
ORGANISM(S): Danio rerio 
2005-09-16 | E-GEOD-3303 | biostudies-arrayexpress
TranscriptomicsSkeletal muscle gene expression data from Down syndrome mice
Persons with Down syndrome (DS) exhibit low muscle strength that significantly impairs their physical functioning. The Ts65Dn mouse model of DS also exhibits muscle weakness in vivo and may serve as a useful model to examine potential factors responsible for DS-associated muscle dysfunction. Therefo...
ORGANISM(S): Mus musculus 
2013-01-06 | E-GEOD-39159 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of whole substantia nigra in Parkinson's disease
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects Published work contains more information on Parkinson and Control groups
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20292 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of putamen in Parkinson's disease
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects Published work contains more information on Parkinson and Control groups
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20291 | biostudies-arrayexpress
TranscriptomicsComparison of Environmental and Genetic models of ADHD
ADHD is the most common neurobehavioral disorder in school-aged children. In addition to genetic factors, environmental influences or gene x environmental interactions also play an important role in ADHD. One example of a well studied environmental risk factor for ADHD is exposure to polychlorinated...
ORGANISM(S): Rattus norvegicus 
2008-11-20 | E-GEOD-12457 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of prefrontal area 9 in Parkinson's disease
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects Published work contains more information on Parkinson and Control groups
ORGANISM(S): Homo sapiens 
2010-02-22 | E-GEOD-20168 | biostudies-arrayexpress
TranscriptomicsExpression analysis of laser-dissected SNpc neurons in Parkinson's disease
Genome-wide transcriptome analysis of expression changes in laser-dissected SNpc neurons from Parkinson's disease brain tissue versus control brain tissue. Post-mortem brain expression analysis performed in 10 PD brain samples and 8 control brain samples.
ORGANISM(S): Homo sapiens 
2010-02-22 | E-GEOD-20141 | biostudies-arrayexpress
Sort   by:  
 Page size