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TranscriptomicsComparison of two hepatocellular cancer cell lines with distinct properties regarding epithelial-mesenchymal transition
The epithelial to mesenchymal transition (EMT) of malignant hepatocytes is a crucial event in hepatocellular carcinoma (HCC) progression and recurrence. We aimed to establish a human model of EMT to examine drug efficacy and specificity in HCC progression. Human HCC cell populations were characteriz...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-26391 | biostudies-arrayexpress
ProteomicsGas6/Axl signaling activates Akt in liver cancer cells
We investigated which signaling pathways downstream of Gas6/Axl promote the invasive phenotype of liver cancer cells. Thus, we performed phospho-proteomic analysis of MR hepatocytes and those expressing Axl (MR-Axl) in the presence and absence of Gas6. Protein-clustering based on the pattern of phos...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-23 | PXD047577 | Pride
Cell invasion Axl Hepatocellular carcinoma. Gas6 
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