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This SuperSeries is composed of the following subset Series: GSE21298: Profiling wt SOD versus ALS SOD1(G93A) mutant GSE21305: Profiling neuroblastoma SH-SY5Y with Paraquat treatment Mitochondrial dysfunction has been directly or indirectly implicated in the pathogenesis of a number of neurodegener...
ORGANISM(S): Homo sapiens 
Alzheimer’s disease (AD) is the most common neurodegenerative pathology affecting more than 20 million people worldwide and the leading cause of dementia. Although AD neuropathology has been well defined, the underlying causes of the disease remain debatable. Recently, sex and gender are emerging as...
ORGANISM(S): Homo sapiens (Human) 
2024-10-01 | PXD034137 | Pride
Infectious mastitis by non-aureus staphylococci (NAS) is a significant issue in dairy buffalo farming. In a herd with subclinical NAS mastitis, we identified Staphylococcus microti as the predominant species by MALDI-TOF mass spectrometry. To assess milk protein integrity and investigate potential d...
ORGANISM(S): Bubalus bubalis 
2022-06-09 | PXD028793 | Pride
Experimental evidence suggests that environmental stress conditions can alter the expression of BDNF and the levels of this neurotrophin influence the behavioural response in mammalian models. Recently it has been demonstrated that the exposure to 34° C for 21 days alters the brain proteome and beha...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-06-09 | PXD030733 | Pride
The etiopathogenesis of obesity-related chronic kidney disease (CKD) is still scarcely understood. Aim of this study is to shed light on the molecular pathogenesis of obesity-induced CKD by assessing the effect of high fat diet (HF) on molecular pathways leading to organ damage, steatosis, and fibro...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD031915 | Pride
Olfaction and chemical communication are fundamental for coordination in insect societies, especially in species forming large colonies. Reproductive and task partitioning suggest that colony members belonging to different castes or subcastes or performing different tasks during their life (polyethi...
ORGANISM(S): Apis mellifera (Honeybee) 
2018-06-12 | PXD009062 | Pride
Whole-genome profiling of SH-SY5Y cells was done on neuroblastoma SH-SY5Y stably transfected with cDNAs coding for SOD1WT or the mutant SOD1(G93A) protein. Five wt SOD versus five mutant SOD
ORGANISM(S): Homo sapiens 
SAGE performed on biopsies of Barrett's esophagus, squamous esophagus and gastric cardia taken from a metaplastic Barrett's esophagus patient. Keywords: SAGE comparative analysis of gene expression profiles of Barrett's esophagus, normal squamous esophagus and gastric cardia tissue
ORGANISM(S): Homo sapiens 
Allogrooming is a behaviour in which a worker uses its mouth parts to remove debris from the body of other colony members. This behaviour, observed in several species of eusocial insects, play a role in defence against parasites and pathogens. In honeybees, allogrooming represents an important resis...
ORGANISM(S): Apis mellifera (Honeybee) 
2020-06-08 | PXD017651 | Pride
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