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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
TranscriptomicsTranscription profiling of 22 Pancreatic Cancer Cell Lines
We used microarrays to analyze the global expression patterns for 22 commercially available pancreatic cancer cell lines 22 pancreatic cancer cell lines were grown to 80% confluence in DMEM/FBS/PenStrep media and then harvested for total RNA
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21654 | biostudies-arrayexpress
TranscriptomicsMolecular Signatures of Neurogenesis in the Hippocampal Subgranular Zone of Rodents
We sought to find molecular signatures of the SGZ cell types, and to characterize the molecular pathways and transcription factor cascades that define the neurogenic niche. We used laser capture microdissection and DNA microarrays to profile gene expression in the inner (SGZ) and outer portions of t...
ORGANISM(S): Mus musculus 
2013-12-04 | E-GEOD-39697 | biostudies-arrayexpress
UnknownReduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriers.
Not available
S-EPMC5837795 | biostudies-literature
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsParadigm Test Set
This SuperSeries is composed of the following subset Series: GSE35186: Paradigm Test Set Expression Array GSE35189: Paradigm Test Set aCGH Array Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-06-20 | E-GEOD-35191 | biostudies-arrayexpress
TranscriptomicsBRC77 Agilent Gene Expression Arrays
Agilent 44K whole genome studies were used to correlate gene expression values with mutations found in massively parallel sequencing experiments. 77 patients were profiled using Agilent's two-color microarray platform. Tumor(cy5) was co-hybridized to a reference(cy3).
ORGANISM(S): Homo sapiens 
2012-06-20 | E-GEOD-29442 | biostudies-arrayexpress
UnknownClinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study.
Not available
S-EPMC10637772 | biostudies-literature
TranscriptomicsPre-Collaborative Cross liver gene expression
The Collaborative Cross (CC) recombinant inbred panel was conceived as an ideal resource for mammalian system genetics. The pre-CC is a proof-of-concept experiment involving CC lines that have undergone at least five generations of inbreeding. Siblings from these lines were each involved in one of...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-22297 | biostudies-arrayexpress
UnknownThe cognitive and behavioral phenotype of the 16p11.2 deletion in a clinically ascertained population.
Not available
S-EPMC5410712 | biostudies-literature
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