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TranscriptomicsMap transformed DNA into W6G from VCXB21
Vibrio cholerae isolate W6G transformed with DNA from VCXB21 and selected for chitosan metabolism. Nine independent transformants compared to parental W6G on microarrays containing probes for all N16961 ORFs. Regions acquired from VCXB21 hybridize more strongly to the array. A genotyping experimen...
ORGANISM(S): Vibrio cholerae 
2007-08-16 | E-GEOD-8791 | biostudies-arrayexpress
UnknownStructural characterization of Campylobacter jejuni lipooligosaccharide outer cores associated with Guillain-Barre and Miller Fisher syndromes.
Not available
S-EPMC1828588 | biostudies-literature
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
TranscriptomicsRNA-seq comparison of fetal lung and cultured fetal lung derived organoids with pluripotent stem cell derived lung organoids
Underdeveloped lungs are the primary cause of death in premature infants, however, little is known about stem and progenitor cell maintenance during human lung development. In this study, we have identified that FGF7, Retinoic Acid and CHIR-99021, a small molecule that inhibits GSK3 to activate Wnt ...
ORGANISM(S): Homo sapiens 
2018-11-17 | E-MTAB-6023 | biostudies-arrayexpress
TranscriptomicsInduced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects.
Multiple FTD patient-specific iPSC lines were generated for the first time, Human neurons of progranulin haploinsufficiency have been established. PGRN S116X neurons are more sensitive to kinase inhibitors-induced cell stress, which can be rescued by ectopic progranulin expression, revealing progran...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-40378 | biostudies-arrayexpress
UnknownQuantifying regional α -synuclein, amyloid β, and tau accumulation in lewy body dementia.
Not available
S-EPMC8862415 | biostudies-literature
ProteomicsCharacterization of Mast2 Kinase Defines Structural Features, Regulation, and Substrates
The mammalian microtubule-associated serine/threonine (MAST) kinases are a highly conserved subfamily of AGC kinases that are implicated as therapeutic targets for cancer and diabetes. However, the activity, regulation, and substrates of MAST kinases are poorly understood. Stable 18O-ATP labeled kin...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD069171 | Pride
Human Mast2 Sikalip 
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
Not available
S-EPMC10600726 | biostudies-literature
UnknownRevised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup.
Not available
S-EPMC11350039 | biostudies-literature
MetabolomicsELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...
2024-04-02 | MTBLS9418 | MetaboLights
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