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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
TranscriptomicsTU-tagging: cell type specific RNA isolation from intact complex tissues
We show that the combination of spatially restricted uracil phosphoribosyltransferase (UPRT) expression with 4-thiouracil (4TU) delivery can be used to label and purify cell type specific RNA from intact complex tissues. This method is useful for isolating RNA from cell types that are difficult to i...
ORGANISM(S): Drosophila melanogaster 
2010-06-19 | E-GEOD-15445 | biostudies-arrayexpress
UnknownOxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution: Part 3 of a 3-Part Series.
Not available
S-EPMC5568826 | biostudies-literature
UnknownLate Systolic Myocardial Loading Is Associated With Left Atrial Dysfunction in Hypertension.
Not available
S-EPMC5484079 | biostudies-literature
TranscriptomicsCharacterization of Calprotectin treated medium
The goal of this study is to correlate the transcriptional response of S. aureus cells grown in Calprotectin treated medium with that of cells grown in Mn or Zn depletion conditions. Keywords: RNA sample Staphylcoccus aureus strain Newman was grown to mid-log phase in Calprotectin treated medium or ...
ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman 
2010-05-26 | E-GEOD-9828 | biostudies-arrayexpress
MetabolomicsELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...
2024-04-02 | MTBLS9418 | MetaboLights
UnknownIdentification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
Not available
S-EPMC9857322 | biostudies-literature
UnknownExperimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses.
Not available
S-EPMC8074517 | biostudies-literature
ProteomicsProteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia
A deep-scale proteome and phosphoproteome database from 44 representative Acute Myeloid Leukemia (AML) patients from the LAML TCGA dataset, and 6 healthy bone marrow derived controls including 3 lineage-depleted and 3 CD34+ selected bone marrows.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-07 | MSV000089012 | MassIVE
ProteomicsProteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia
Deep-scale proteome and phosphoproteome protocol benchmark.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-10 | MSV000089035 | MassIVE
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