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TranscriptomicsRNA-seq of human prostate cancer cell line with IRF7 knock-down treated with radiation against wild-type control
Abstract/Project overview Tumour recurrence can be influenced by the mutational status of a tumour but also how the tumour responds to therapy. Whilst activation of Type 1 interferon signalling is a hallmark of how cells respond to viral infection, in cancer cells, multiple stresses are known to a...
ORGANISM(S): Homo sapiens 
2023-07-01 | E-MTAB-9286 | biostudies-arrayexpress
UnknownCombined estimation of disease progression and retention on antiretroviral therapy among treated individuals with HIV in the USA: a modelling study.
Not available
S-EPMC6693664 | biostudies-literature
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
UnknownALK: a tyrosine kinase target for cancer therapy.
Not available
S-EPMC5171696 | biostudies-literature
UnknownReporting and design of randomized controlled trials for COVID-19: A systematic review.
Not available
S-EPMC7834682 | biostudies-literature
MetabolomicsAzithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation
Administration of azithromycin after allogeneic hematopoietic stem cell transplantation for hematological malignancies has been associated with relapse in a randomized phase 3 controlled clinical trial. Studying 240 samples from patients randomized in this trial is a unique opportunity to better und...
2022-08-22 | MTBLS406 | MetaboLights
MetabolomicsMetabolomics Insights in Early Childhood Caries
Dental caries is characterized by a dysbiotic shift at the biofilm-tooth surface interface, yet comprehensive biochemical characterizations of the biofilm are scant. We used metabolomics to identify biochemical features of the supragingival biofilm associated with early childhood caries (ECC) preval...
2021-01-29 | MTBLS2215 | MetaboLights
UnknownIRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.
Not available
S-EPMC6345973 | biostudies-literature
UnknownImplementation of Basal-Bolus Therapy in Type 2 Diabetes: A Randomized Controlled Trial Comparing Bolus Insulin Delivery Using an Insulin Patch with an Insulin Pen.
Not available
S-EPMC6532545 | biostudies-literature
UnknownCOVID-19 highlights the need to improve resilience and equity in managing small-scale fisheries.
Not available
S-EPMC11659175 | biostudies-literature
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