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ProteomicsMin protein in vitro protein expression kinetics
The Min biochemical network regulates bacterial cell division and is a prototypical example of self-organizing molecular systems. Cell-free assays relying on purified proteins have shown that MinE and MinD self-organize into surface waves on a planar membrane and into various oscillatory patterns in...
ORGANISM(S): Escherichia Coli 
2019-11-11 | PXD015686 | panorama
TranscriptomicsRNA Affymetrix microarray analysis of colonic mucosal layer of Apc Min/+ mice fed or not with maslinic acid.
This experiment reports the RNA microarray data from the microarray analysis performed to the RNA isolated from colonic mucosal layer of Apc Min/+ mice. Apc Min/+ mice develop polyps in both the small and large intestine, with a greater incidence of intestinal adenomas observed in the former. We wan...
ORGANISM(S): Mus musculus 
2015-10-31 | E-MTAB-4007 | biostudies-arrayexpress
MetabolomicsIntegrated transcriptomic and metabolomic analysis reveals the metabolic programming of GM-CSF-and M-CSF-differentiated mouse macrophages

Macrophages play a critical role in the inflammatory response and tumor development. Macrophages are primarily divided into pro-inflammatory M1-like and anti-inflammatory M2-like macrophages based on their activation status and functions. In vitro macrophage models could be derived from ...

2023-09-19 | MTBLS6502 | MetaboLights
ProteomicsInner membrane proteome of E. coli Min mutant
In bacteria, proteins of the MinD/ParA superfamily are reported to partition DNA and protein complexes to designate subcellular location. Among them, the E. coli Min system is a prominent example to demonstrate that the protein function is spatially regulated by the dynamic subcellular localization ...
ORGANISM(S): Escherichia coli 
2016-02-23 | PXD002548 | Pride
Cell division The min system Itraq E. coli Membrane 
TranscriptomicsTranscription profiling of hearts from young (2-4 month) and moderately aged (16-18 month) C57/Bl6 male mice subjected to i) 20 min global ischaemia, 60 min reperfusion or ii) 80 min aerobic perfusion/normoxia
Hearts from young (2-4 month) and moderately aged (16-18 month) C57/Bl6 male mice were subjected to i) 20 min global ischaemia, 60 min reperfusion or ii) 80 min aerobic perfusion/normoxia.
ORGANISM(S): Mus musculus 
2005-12-31 | E-MEXP-496 | biostudies-arrayexpress
TranscriptomicsNon-tumor/tumor intestinal tissue of control or intestine-specific HAI-1 deficient Apc(Min/+) mice
To analyse roles of HAI-1/Spint1 in intestinal tumorigenesis, we examined the effect of intestine-specific deletion of Spint1 gene on Apc(Min/+) mice. The loss of Hai-1/Spint1 significantly accelerated tumor formation in ApcMin/+ mice and shortened their survival periods. Mouse small intestine tumor...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-40856 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of Salmonella during lag, exponential and stationary phases of growth
Transcriptional profiles during all phases of growth of Salmonella Typhimurium SL1344 were obtained and used to investigate growth phase-dependent alterations in gene expression. Viable count growth curve analysis of the growth system showed a culture lag time of 2.09 hours, and profiles at 4, 20, 4...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2011-12-13 | E-GEOD-22294 | biostudies-arrayexpress
MetabolomicsM12-24 metabolome of dairy cow

This study conducted non-targeted metabolomic analysis on rumen fluid from 24 dairy cows fed with M12 additive, aiming to comprehensively profile changes in endogenous metabolites and elucidate the mechanism by which M12 modulates rumen function.

2025-10-21 | MTBLS12930 | MetaboLights
TranscriptomicsGm heat 30 min & 5 h
control plants vs heat treated plants (30 min & 5 h)
ORGANISM(S): Glycine max 
2015-08-12 | E-MTAB-2852 | biostudies-arrayexpress
MetabolomicsGPR109a-AMPK Axis Mediates the Attenuation of Uric Acid-Induced M1 Macrophage Polarization by β-hydroxybutyrate from Lacticaseibacillus rhamnosus M2b

Hyperuricemia (HUA) is a metabolic disorder marked by increased blood uric acid (UA) levels, closely linked to conditions such as gout. UA-induced macrophage M1 polarization fundamentally exacerbates inflammatory pathophysiology, but current HUA-specific immunoregulatory treatments are inadequat...

2026-01-26 | MTBLS13224 | MetaboLights
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