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MetabolomicsMetabolic memory underlying minimal residual disease in breast cancer

Tumor relapse from treatment-resistant cells (minimal residual disease, MRD) underlies most breast cancer related deaths. Yet, the molecular characteristics defining their malignancy have largely remained elusive. Here we integrated multi-omics data from a tractable organoid system with a metabol...

2021-09-14 | MTBLS1507 | MetaboLights
MetabolomicsMinimal change disease and focal segmental sclerosis in urine
Not available
ORGANISM(S): Homo sapiens 
ST000329 | MetabolomicsWorkbench
TranscriptomicsComparison of Glomerular Transcriptome Profiles of Adult-Onset Steroid Sensitive Focal Segmental Glomerulosclerosis and Minimal Change Disease
To search for biomarkers to differentiate Adult-Onset Steroid Sensitive focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). Compared the profiles of glomerular transcriptomes between patients with FSGS and patients with MCD using microarray analysis. This dataset is part of ...
ORGANISM(S): Homo sapiens 
2017-01-04 | E-GEOD-69814 | biostudies-arrayexpress
Metabolomics13C metabolomics reveals widespread change in carbon fate during coral bleaching
INTRODUCTION: Rising seawater temperatures are threatening the persistence of coral reefs; where above critical thresholds, thermal stress results in a breakdown of the coral-dinoflagellate symbiosis and the loss of algal symbionts (coral bleaching). As symbiont-derived organic products typically fo...
2018-12-04 | MTBLS538 | MetaboLights
MetabolomicsProteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation

Saccharomyces cerevisiae is a widely used cell factory; therefore, it is important to understand how it organizes key functional parts when cultured under different conditions. Here, we perform a multiomics analysis of S. cerevisiae by culturing the strain with a wide range of s...

2022-08-31 | MTBLS697 | MetaboLights
ProteomicsLaser microdissection and mass spectrometry shows loss of podocyte proteins in minimal change disease and focal segmental glomerulosclerosis.
Minimal change disease and primary focal segmental glomerulosclerosis (FSGS) are common causes of nephrotic syndrome. Both diseases present with massive proteinuria and widespread foot process effacement on electron microscopy examination. On the other hand, secondary FSGS can also present with sign...
ORGANISM(S): Homo sapiens (Human) 
2025-12-29 | PXD057165 | Pride
Laser microdissection Focal segmental glomerulosclerosis Mass spectrometry Minimal change disease 
ProteomicsPathogenesis of focal segmental glomerulosclerosis and minimal change disease
Podocyte injury is the hallmark of both focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) and is ultimately reflected in foot process effacement proteinuria. Triggers and pathogenic pathways leading to podocyte cytoskeleton rearrangements are however incompletely explained. ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-03-12 | MSV000097297 | MassIVE
TranscriptomicsGene expression profiling of peripheral blood mononuclear cells from patients with minimal change nephrotic syndrome
Background: Minimal change nephrotic syndrome (MCNS) is considered to be associated with T cell dysfunction, via unknown mechanisms. Experimental observations suggest that some humoral factors alter the permeability of glomerular filtration barrier. However, the nature of such factors remains still ...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-7349 | biostudies-arrayexpress
GenomicsIdiopathic membranous nephropathy and minimal change disease (MCD) transcriptome
Idiopathic membranous nephropathy and minimal change disease (MCD) transcriptome
PRJNA895478 | ENA
ProteomicsAnti-nephrin autoantibodies in minimal change disease and focal segmental glomerulosclerosis (proteomics)
Background: Minimal change disease (MCD) and focal-segmental glomerulosclerosis (FSGS) are immune-mediated glomerular diseases manifesting as nephrotic syndrome. Autoantibodies against the podocyte slit diaphragm protein nephrin were recently identified in a subset of patients with minimal change di...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-27 | PXD047417 | Pride
Focal segmental glomerulosclerosis (fsgs) Proteomics Minimal change disease (mcd) Autoantibodies Phospho-proteomics Kidney disease Nephrin 
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