Sort   by:  
 Page size 
UnknownLaboratory investigations into the origin of Mycoplasma synoviae isolated from a lesser flamingo (Phoeniconaias minor).
Not available
S-EPMC4788927 | biostudies-literature
TranscriptomicsRocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor
Rocaglamide A (RocA) typifies a class of protein synthesis inhibitors that selectively kill aneuploid tumor cells and repress translation of specific mRNAs. RocA targets eukaryotic initiation factor 4A (eIF4A), an ATP-dependent DEAD-box RNA helicase; its mRNA selectivity is proposed to reflect highl...
ORGANISM(S): synthetic construct 
2016-06-15 | E-GEOD-79392 | biostudies-arrayexpress
TranscriptomicsRocaglamide A converts RNA helicase eIF4A into a sequence-specific translational repressor
Rocaglamide A (RocA) typifies a novel class of protein synthesis inhibitors that selectively kill aneuploid tumor cells and repress translation of specific mRNAs. RocA targets eukaryotic initiation factor 4A (eIF4A), the prototypical DEAD-box RNA helicase, and its mRNA selectivity is proposed to ref...
ORGANISM(S): synthetic construct 
2016-06-15 | E-GEOD-70211 | biostudies-arrayexpress
ProteomicsAbsolute abundance of human crystallins in lens
Purpose: Measurement of crystallin abundances in human lens has previous relied on poorly reproducible electrophoretic separations or only semi-quantitative mass spectrometry. Therefore, isotope labeled standards were created for all major human lens crystallins so that their absolute abundances cou...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD053890 | panorama
ProteomicsImprovements in glycoproteomics through architecture changes to the Orbitrap Tribrid MS platform
Hardware changes introduced on the Orbitrap Ascend MultiOmics Tribrid MS include dual ion routing multipoles (IRMs) that can enable parallelized accumulation, dissociation, and Orbitrap mass analysis of three separate ion populations. The balance between these instrument functions is especially impo...
ORGANISM(S): Homo sapiens (Human) 
2025-09-14 | PXD058153 | Pride
N-glycopeptides Fragmentation Glycoproteomics Tandem mass spectrometry O-glycopeptides Electron transfer dissociation 
TranscriptomicsRNA-seq of Chlamydomonas reinhardtii under diel conditions to identify cycling genes
Biological rhythms in response to both endogenous (circadian) and exogenous (e.g. diel) cycles, with a period of ~24 hours, are a prominent feature of many living systems. In green algal species, knowledge on the extent of diel rhythmicity of genome wide gene expression, its evolution, and its cis-r...
ORGANISM(S): Chlamydomonas reinhardtii 
2014-10-25 | E-GEOD-62671 | biostudies-arrayexpress
TranscriptomicsImporatance of substantial weight loss for altering gene expression during intensive cardiovascular lifestyle modification
The objective of this study was to examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles. Substantial weight loss (-15.2+3.8%) in lifestyle participants was associated with improvement in selected cardiovascular risk factors and signific...
ORGANISM(S): Homo sapiens 
2015-02-21 | E-GEOD-66175 | biostudies-arrayexpress
UnknownCrystal structures of penicillin-binding protein 2 from penicillin-susceptible and -resistant strains of Neisseria gonorrhoeae reveal an unexpectedly subtle mechanism for antibiotic resistance.
Not available
S-EPMC2613624 | biostudies-literature
MetabolomicsRare and common genetic determinants of metabolic individuality and their effects on human health (EPIC-Norfolk study assays)

Garrod’s concept of “chemical individuality” has contributed to comprehension of the molecular origins of human diseases. Untargeted high-throughput metabolomic technologies provide an in-depth snapshot of human metabolism at scale. We studied the genetic architecture of the human plasma metabolo...

2022-09-09 | MTBLS833 | MetaboLights
TranscriptomicsMethylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia.
Background: Schizophrenia is a severe neuropsychiatric disorder that is hypothesized to result from disturbances in early brain development, and there is mounting evidence to support a role for developmentally-regulated epigenetic variation in the molecular etiology of the disorder. Here, we describ...
ORGANISM(S): Homo sapiens 
2014-09-13 | E-GEOD-61380 | biostudies-arrayexpress
Sort   by:  
 Page size