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TranscriptomicsmiRNA expressions in non-cancerous and cancerous human gastric tissues
We investigated the involvement of microRNAs (miRNAs) in gastric cancers. MiRNA expression was profiled from 40 cancerous and 40 non-cancerous tissues obtained from the National Cancer Centre, Singapore, and Singhealth Tissue Repository, Singapore. We identified 80 differentially expressed miRNA...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-23739 | biostudies-arrayexpress
ProteomicsMechanisms associated with systemic effects of cancer
Cancer is considered as a disease of a specific organ, but its effects are felt throughout the body. The systemic effects of cancer can lead to weakness in muscles and heart, which hastens cancer-associated death. miR-486 is a myogenic microRNA and its reduced expression in skeletal muscle is observ...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-19 | PXD028554 | Pride
Breast cancer Lc-msms Mouse Functional limitations Skeletal muscle Mir-486 
GenomicsEffect of overexpression on miR-486-5p in Healthy doncor CD34+ cells
Effect of overexpression on miR-486-5p in Healthy doncor CD34+ cells
PRJNA588165 | ENA
TranscriptomicsGene expression profile (GEP) of miR-486-3p overexpressing CD34+ HPCs
The transcription factor c-Myb plays a key role in human primary CD34+ hematopoietic progenitor cells (HPCs) lineage choice, by enhancing erythropoiesis at the expense of megakaryopoiesis. We previously demonstrated that c-Myb affects erythroid versus megakaryocyte lineage decision in part by transa...
ORGANISM(S): Homo sapiens 
2015-08-07 | E-GEOD-60298 | biostudies-arrayexpress
GenomicsRNA-seq reveals differential expression of potential miR-486 target transcripts
RNA-seq reveals differential expression of potential miR-486 target transcripts
PRJNA655625 | ENA
GenomicsmiR-486-5p inhibits eNOS and angiogenesis in cultured endothelial cells by targeting MAML3
miR-486-5p inhibits eNOS and angiogenesis in cultured endothelial cells by targeting MAML3
PRJNA1181906 | ENA
GenomicsmiR-486 is an epigenetic modulator of Duchenne muscular dystrophy pathologies [RNA-seq]
miR-486 is an epigenetic modulator of Duchenne muscular dystrophy pathologies [RNA-seq]
PRJNA740320 | ENA
OthermiR-486-5p inhibits eNOS and angiogenesis in cultured endothelial cells by targeting MAML3
Kidney ischemia-reperfusion injury (IR) is associated with endothelial injury. Administration of miR-486-5p protects against rat kidney IR injury, with localization to capillary endothelial cells, although it inhibits IR-induced endothelial nitric oxide synthase (eNOS) protein expression. We studied...
ORGANISM(S): Homo sapiens 
2025-06-04 | GSE281065 | GEO
TranscriptomicsGene expression profile (GEP) of miR-486-3p overexpressing CD34+ HPCs
The transcription factor c-Myb plays a key role in human primary CD34+ hematopoietic progenitor cells (HPCs) lineage choice, by enhancing erythropoiesis at the expense of megakaryopoiesis. We previously demonstrated that c-Myb affects erythroid versus megakaryocyte lineage decision in part by transa...
ORGANISM(S): Homo sapiens 
2015-08-07 | GSE60298 | GEO
TranscriptomicsmiR-486 is an epigenetic modulator of Duchenne muscular dystrophy pathologies [RNA-seq]
Duchenne muscular dystrophy (DMD) is an X-linked progressive muscle disorder resulting in muscle weakness and cardiomyopathy. MicroRNAs have shown to play a significant role in muscle development, metabolism, and disease pathologies. We demonstrated that miR-486 expression is reduced in DMD muscles ...
ORGANISM(S): Mus musculus 
2022-10-01 | GSE178772 | GEO
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