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ProteomicsMassProteomic Analysis of MIRO2 Interacting Proteins by Co-IP and Mass Spectrometry
This project investigates the interactome of MIRO2 using co-immunoprecipitation (Co-IP) followed by mass spectrometry analysis. Control and MIRO2-FLAG overexpressing cells were subjected to Co-IP to identify proteins that interact with MIRO2 and potentially facilitate mitochondrial-derived vesicle (...
ORGANISM(S): Homo sapiens (Human) 
2026-06-03 | PXD078488 | Pride
Human Miro2-flag B-fission 
ProteomicsIdentification of novel protein binders of human MIRO2 in prostate cancer
In previous studies, we showed that MIRO2 mRNA is up-regulated in primary cancer versus normal tissues, across multiple tumor types. MIRO2 had been previously studied in the context of non-tumorigenic cells, where it coordinates microtubule- and actin-based mitochondrial movement. However, we showed...
ORGANISM(S): Homo sapiens (Human) 
2021-11-25 | PXD029490 | Pride
Cancer Protein interaction Mitochondria Signaling 
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