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Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
Unknown#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol.
Not available
S-EPMC8609898 | biostudies-literature
TranscriptomicsTranscription profiling of livers from Low Density Lipoprotein Receptor null mice expressing human LXR alpha to explore the molecular basis of metabolic effects of increased hepatic hLXR alpha.
Microarray analysis of liver RNA from male Low Density Lipoprotein Receptor null mice on C57B6 background expressing human LXR alpha or GFP (control) via adeno-associated virus (AAV2.8) gene transfer, under control of the liver specific human thyroxine binding globulin promoter. Samples are from 8 m...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2644 | biostudies-arrayexpress
ProteomicsConstruction, debugging and iterative redesign of synXVI, a 903-kb synthetic chromosome of Saccharomyces cerevisiae
Assembly and debugging of the 902,994-bp synthetic Saccharomyces cerevisiae chromosome synXVI of the Sc2.0 project is described. Application of the CRISPR D-BUGS protocol identified defective loci, which were modified to improve sporulation and recover wild-type like growth when grown on glycerol as...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-05-07 | PXD058199 | Pride
Yeast 2.0 Scramble Synthetic genome Yeast 
UnknownAntibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain.
Not available
S-EPMC8608564 | biostudies-literature
MetabolomicsLongitudinal Deep Multi-Omics Profiling in aCLN3Δex7/8Minipig Model Reveals Novel Biomarker Signatures for Batten Disease
Development of therapies for CLN3 Batten disease, a rare pediatric lysosomal storage disorder, has been hindered by the lack of etiological insights and translatable biomarkers to clinics. Here, we used a deep multi-omics approach to discover new biomarkers using longitudinal serum samples from a po...
2025-08-13 | MTBLS1107 | MetaboLights
UnknownMutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study.
Not available
S-EPMC10599647 | biostudies-literature
UnknownEvaluating the implementation and impact of navigator-supported remote symptom monitoring and management: a protocol for a hybrid type 2 clinical trial.
Not available
S-EPMC9027833 | biostudies-literature
GenomicsRomidepsin and azacitidine synergize in their epigenetic modulatory effects to induce apoptosis in CTCL
We demonstrate that the combination of the HDAC inhibitor, romidepsin, and the demethylating agent, azacitidine, exerts synergistic anti-proliferative effects and induction of apoptosis involving activation of the caspase cascade in CTCL cell lines as well as CD4+ T cells derived from patients with ...
ORGANISM(S): Homo sapiens 
2016-03-30 | E-GEOD-66732 | biostudies-arrayexpress
UnknownDeterminants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naive healthcare workers.
Not available
S-EPMC8752368 | biostudies-literature
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