Sort   by:  
 Page size 
ProteomicsMPP profiling in yeast - Quantitative profiling for substrates of the mitochondrial presequence processing protease reveals a set of non-substrate proteins increased upon proteotoxic stress
The majority of mitochondrial preproteins is targeted via N-terminal presequences that are cleaved upon import into the organelle. The essential mitochondrial processing protease (MPP) is assumed to cleave the majority of incoming precursors. However, only few substrate proteins of MPP have been exp...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-10-14 | PXD002063 | Pride
Mitochondrial processing protease mpp Mitochondria Chafradic Mitochondrial stress response Presequence import pathway 
UnknownThe novel mitochondrial matrix protease Ste23 is required for efficient presequence degradation and processing.
Not available
S-EPMC5391191 | biostudies-literature
UnknownAutocatalytic processing of m-AAA protease subunits in mitochondria.
Not available
S-EPMC2754935 | biostudies-literature
UnknownMitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
Not available
S-EPMC3321149 | biostudies-literature
UnknownSubstrate recognition by the human mitochondrial processing peptidase and its processing of PINK1.
Not available
S-EPMC12670562 | biostudies-literature
ProteomicsProteolytic processing promotes the decatenation activity of human mitochondrial TOP3A; BioID
The TOP3A gene encodes protein products that are targeted to both the nucleus and to mitochondria. The nuclear isoform of TOP3A is required for the resolution of double Holliday junctions during homologous recombination, while the mitochondrial isoform of TOP3A separates hemicatenated daughter mitoc...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD063285 | Pride
Top3a Label-free Bioid 
UnknownMutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood.
Not available
S-EPMC5985287 | biostudies-literature
UnknownMitochondrial Processing Peptidases-Structure, Function and the Role in Human Diseases.
Not available
S-EPMC8835746 | biostudies-literature
UnknownPPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients.
Not available
S-EPMC10415619 | biostudies-literature
UnknownThe Evolutionary History of Peptidases Involved in the Processing of Organelle-Targeting Peptides.
Not available
S-EPMC9291397 | biostudies-literature
Sort   by:  
 Page size