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GenomicsRole of mitofusins in oocyte development
Role of mitofusins in oocyte development
PRJNA602461 | ENA
GenomicsModulating mitofusins to control mitochondrial function and signaling
Modulating mitofusins to control mitochondrial function and signaling
PRJNA776819 | ENA
ProteomicsProximity tagging identified mitofusins stimulating mitochondria and peroxisomes clustering
we applied a proximity tagging system PUP-IT to PEX ubiquitin ligase to identify their proximal proteins. Surprisingly, we identified many mitochondrial proteins in the proximity of peroxisomes. We further validated the interaction between PEX and mitofusins (MFNs).
ORGANISM(S): Homo Sapiens 
2022-03-19 | PXD032661 |
TranscriptomicsModulating mitofusins to control mitochondrial function and signaling
Purpose: Mitofusin regulate the fusion of the outer mitochondrial membrane. MASM7 is an activator of mitofusins, which promotes mitochondrial fusion. Whereas, MFI8 is an inhibitor of mitofusins, which inhibits mitochondrial fusion, and subsequently promotes mitochondrial fission. The goal of this st...
ORGANISM(S): Mus musculus 
2022-06-21 | GSE186924 | GEO
TranscriptomicsRole of mitofusins in oocyte development
We performed RNA sequencing (RNAseq) analysis to determine the effect of single (Mfn1-/- or Mfn2-/-) and double (Mfn1-/- and Mfn2-/-; Mfn1&2-/-) knockouts of mitofusins on oocyte gene expression profile. We found that in comparison with the wild-type (WT) control, 161 (Mfn1-/-), 538 (Mfn2-/-) and 47...
ORGANISM(S): Mus musculus 
2026-01-11 | GSE143992 | GEO
UnknownModulating mitofusins to control mitochondrial function and signaling.
Not available
S-EPMC9262907 | biostudies-literature
UnknownRecent insights into the structure and function of Mitofusins in mitochondrial fusion.
Not available
S-EPMC6317495 | biostudies-literature
UnknownMutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts.
Not available
S-EPMC3050809 | biostudies-literature
UnknownMitofusins: from mitochondria to fertility.
Not available
S-EPMC9209398 | biostudies-literature
GenomicsMitofusins Regulate Lipid Metabolism to Mediate the Development of Lung Fibrosis
Mitofusins Regulate Lipid Metabolism to Mediate the Development of Lung Fibrosis
PRJNA475884 | ENA
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