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TranscriptomicsGenomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease
Evaluation of global expression patterns provides a molecular portrait of mitral valve disease, yields insight into the pathophysiologic aspects of DMVD, and identifies intriguing genes and pathways for further study. (Am J Vet Res 2006;67:1307–1318) Keywords: control vs diseased 4 controls( beagle ...
ORGANISM(S): Canis lupus familiaris 
2008-05-15 | E-GEOD-11460 | biostudies-arrayexpress
TranscriptomicsExpression data from Sus scrofa atria
Regulatory Mechanisms of Atrial Remodeling of Mitral Regurgitation Pigs This study enrolled 6 pigs (age: 18 months) and divided into three groups: mitral regurgitation pigs (MR) (n = 2; 2 males sacrificed 12 months after surgery), MR pigs treated with valsartan (MRV) (n = 2; 2 males age-matched to ...
ORGANISM(S): Sus scrofa 
2015-02-01 | E-GEOD-43072 | biostudies-arrayexpress
ProteomicsIntegration of functional imaging, cytometry and unbiased proteomics reveals new features of endothelial-to-mesenchymal transition in ischemic mitral valve regurgitation in human patients
Background: Following myocardial infarction, mitral regurgitation (MR) is a common complication. Previous animal studies demonstrated the association of endothelial-to-mesenchymal transition (EndMT) with mitral valve (MV) remodeling. Nevertheless, little is known about how MV tissue responds to isch...
ORGANISM(S): Homo sapiens (Human) 
2021-08-13 | PXD025096 | Pride
Human Mitral valve (mv) Proteomic Ischemic mitral regurgitation (imr) Echocardiography Endothelial-to-mesenchymal transition (endmt) Histo-cytometry 
ProteomicsNormal human mitral valve proteome: a preliminary investigation by gel-based and gel-free proteomic approaches
The mitral valve is a highly complex structure which regulates blood flow from the left atrium to the left ventricle (LV) avoiding a significant forward gradient during diastole or regurgitation during systole. The integrity of the mitral valve is also essential for the maintenance of normal LV size...
ORGANISM(S): Homo sapiens (Human) 
2016-08-18 | PXD004397 | Pride
Human normal mitral valve Lc/mse Valvular interstitial cells 
ProteomicsMyocardial proteome profiling reveals disease- and sex-specific alterations in patients with aortic valve stenosis and mitral valve regurgitation
Heart valve diseases, such as aortic valve stenosis (AS) and mitral valve regurgitation (MR), are leading causes of heart failure. However, myocardial proteome studies in AS and MR are extremely rare. We profiled the proteome of 75 human left ventricular myocardial biopsies (AS=41, MR=17, controls=1...
ORGANISM(S): Homo sapiens (Human) 
2022-12-13 | PXD023800 | Pride
Mitral regurgitation Sex differences Cytoskeleton Aortic stenosis Fibrosis Energy metabolism Proteostasis Heart Extracellular matrix 
GenomicsCardiothoracic Surgical Trials Network (CTSN) Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation (SMR)(CTSN-SMR-BioLINCC)
Cardiothoracic Surgical Trials Network (CTSN) Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation (SMR)(CTSN-SMR-BioLINCC)
PRJNA1458273 | ENA
GenomicsCardiothoracic Surgical Trials Network (CTSN) Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation (SMR)(CTSN-SMR-BioLINCC)
Cardiothoracic Surgical Trials Network (CTSN) Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation (SMR)(CTSN-SMR-BioLINCC)
PRJNA1458274 | ENA
GenomicsTranscriptomic analysis of mouse heart after a minimally invasive mitral regurgitation surgery (MiMRS)
Transcriptomic analysis of mouse heart after a minimally invasive mitral regurgitation surgery (MiMRS)
PRJNA1132674 | ENA
GenomicsCardiothoracic Surgical Trials Network (CTSN) Surgical Interventions for Moderate Ischemic Mitral Regurgitation (CTSN-MMR-BioLINCC)
Cardiothoracic Surgical Trials Network (CTSN) Surgical Interventions for Moderate Ischemic Mitral Regurgitation (CTSN-MMR-BioLINCC)
PRJNA1463313 | ENA
GenomicsCardiothoracic Surgical Trials Network (CTSN) Surgical Interventions for Moderate Ischemic Mitral Regurgitation (CTSN-MMR-BioLINCC)
Cardiothoracic Surgical Trials Network (CTSN) Surgical Interventions for Moderate Ischemic Mitral Regurgitation (CTSN-MMR-BioLINCC)
PRJNA1463314 | ENA
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