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ProteomicsLabel-free LC-MSe in tissue and serum reveals protein networks underlying differences between benign and malignant serous ovarian tumors
Purpose: To identify proteins and (molecular/biological) pathways associated with differences between benign and malignant epithelial ovarian tumors. Experimental procedures: Serum of six patients with a serous adenocarcinoma of the ovary was collected before treatment, with a control group consisti...
ORGANISM(S): Homo sapiens (Human) 
2014-10-13 | PXD001084 | Pride
Ovarian cancer Topx peptide quantitation Serum Tissue All ions fragmentation Label free quantitation 
UnknownLabel-free LC-MSe in tissue and serum reveals protein networks underlying differences between benign and malignant serous ovarian tumors.
Not available
S-EPMC4180266 | biostudies-literature
ProteomicsOcotea dataset project - UNIFAL
60 Ocotea crude plant extracts LC-HRMS/DIA-MSe metabolomics data
ORGANISM(S): Ocotea (ncbitaxon:63801) 
MSV000093006 | MassIVE
ProteomicsSnake Venom LC/MSE - Post-transcriptional Mechanisms Contribute Little to Phenotypic Variation in Snake Venoms
Protein expression is a major link in the genotype-phenotype relationship, and processes affecting protein abundances, such as rates of transcription and translation, could contribute to phenotypic evolution if they generate heritable variation. Recent work has suggested that mRNA abundances do not ...
ORGANISM(S): Micrurus fulvius (Eastern coral snake) (Coluber fulvius) Sistrurus miliarius barbouri (Dusky pigmy rattlesnake) (Sistrurus barbouri) Crotalus horridus (Timber rattlesnake) Crotalus adamanteus (Eastern diamondback rattlesnake) Hypsiglena jani Sistrurus catenatus (massasauga) Agkistrodon contortrix Boiga irregularis (Brown tree snake) Micrurus tener (Texas coral snake) Agkistrodon piscivorus (cottonmouth) 
2015-11-09 | PXD002837 | Pride
Snake venom Lc/mse 
ProteomicsA metabolomics perspective on clorobiocin biosynthesis: discovery of bromobiocin and novel derivatives through LC-MSE-based molecular networking
Streptomyces roseochromogenes DS 12.976 was cultivated in DSMZ 65 medium. Clorobiocin and structural analogs were extracted from the supernatant and analyzed via LC-MSE. RAW Files were used to generate Figures 2 and 7.
ORGANISM(S): Streptomyces Roseochromogenes (ncbitaxon:67357) 
2024-01-26 | MSV000093926 | MassIVE
ProteomicsGlobal mapping of rat plasma proteins with a native proteomic approach using nondenaturing micro 2DE and label-free quantitative LC-MS/MS
Plasma samples from adult male rats were separated by nondenaturing micro 2DE and a representative gel was selected, on which a total of 136 CBB-stained spots were numbered and subjected to in-gel digestion and label-free quantitative LC-MSE (MS/MS in data-independent acquisition mode). The analysi...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-10-14 | PXD004395 | Pride
Native proteomics Adult male rat plasma proteome Nondenaturing micro 2de Global mapping Label-free quantitative lc-mse 
ProteomicsPull-down of nuclear proteins from HGC-27 cell line
To identify nuclear proteins that interact with KIT2KIT* G-quadruplex DNA, pull-down assays were performed with nuclear extracts from the KIT-positive HGC-27 cell line. Streptavidin-coated paramagnetic beads were derivatized with the biotinylated oligonucleotide and subsequently incubated with nucle...
ORGANISM(S): Homo sapiens (Human) Streptomyces avidinii 
2022-04-04 | PXD026505 | Pride
Lc-mse Nuclear extracts In-gel tryptic digests Hgc-27 cells Pull-down assays Protein identification 
ProteomicsProteomics in biomanufacturing control: Protein dynamics of CHO-K1 cells and conditioned media during apoptosis and necrosis
Cell viability has a critical impact on product quantity and quality during the biomanufacturing of therapeutic proteins. An advanced understanding of changes in the cellular and conditioned media proteomes upon cell stress and death is therefore needed for improved bioprocess control. Here, a high ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2018-02-27 | PXD008297 | Pride
Proteomics Cho Keywords: biomanufacturing Necrosis Apoptosis 2d-lc-mse 
ProteomicsAnalysis of LDL-associated proteins using the method of digitized native protein mapping
The method of digitized native protein mapping, combining nondenaturing micro 2DE, grid gel-cutting and quantitative LC-MS/MS (in data-independent acquisition mode, or MSE), was improved by using a new MS/MS mode, ion mobility separation enhanced-MSE (HDMSE) and applied to analyze the area of human ...
ORGANISM(S): Homo sapiens (Human) 
2016-05-17 | PXD003720 | Pride
Grid gel-cutting Quantitative lc-hdmse Human plasma low-density lipoprotein Protein-protein interactions Nondenaturing micro 2de Digitized native protein mapping 
ProteomicsLabel-free proteome analysis of plasma from patients with breast cancer: stage-specific protein expression
The breast cancer presents one of the most commonly diagnosed types of cancer among women and its mortality rates remain very high probably due to the diagnosis of this disease is hampered by the lack of an accurate detection method. Since that change of protein expression as well modifications in i...
ORGANISM(S): Homo sapiens (Human) 
2017-02-20 | PXD003106 | Pride
Human Breast cancer Lc-mse Plasma 
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