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To investigate the role of autophagy on cytotoxic CD8 T cells, we developed a new mouse that expresses an Atg5 gene with loxP sites up- and downstream of the exon 3, Cre-recombinase, T cell receptor specific for the OVA peptide SIINFEKL and the congenic marker Thy1.1. These cells were adoptively tra...
ORGANISM(S): Mus musculus 
Immunoprecipitates of FLAG-NEK9 was analyzed to detect interacting proteins under serum starvation conditions.
ORGANISM(S): Mus musculus (Mouse) 
2021-04-09 | PXD024292 | Pride
To identify substrates or adaptors of selective autophagy, we performed a differential interactome screen using wild-type GABARAPL1 and the LIR-docking site mutant GABARAPL1Y49A/N50A,
ORGANISM(S): Homo sapiens (Human) 
2021-04-09 | PXD024290 | Pride
In this study, we conducted a microarray-based analysis to identify differentially expressed miRNAs in CRC by comparing miRNA profiles among primary CRC tissues from patients with liver metastases, primary tissues without liver metastases, and liver metastatic lesions. microRNAs (miRNAs) have been s...
ORGANISM(S): Homo sapiens 
Several innate immune cell subsets have recently been identified to maintain gut homeostasis in both human and mice. Among these subsets, CX3CR1high CD11b+ CD11c+ cells contribute to intestinal tolerance through various mechanisms in mice. However, whether tolerogenic innate myeloid cells are presen...
ORGANISM(S): Mus musculus 
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