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TranscriptomicsWT and Mk2/3 KO MEFs response to etoposide
Primary mouse embryonic fibroblasts (MEFs) from wt and MK2/3 KO mice were treated with 20µM etoposide. Primary MEFs from wt and MK2/3 KO mice were treated with 20µM etoposide and RNA extracted after 1h and 6h.
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-67266 | biostudies-arrayexpress
Proteomicsp38-MK2 signaling axis regulates RNA metabolism after UV light-induced DNA damage
Ultraviolet (UV) light radiation induces the formation of bulky photoproducts in the DNA that interfere with replication and transcription. Recent studies showed that exposure of human cells to UV light globally affects transcription and alternative splicing, however, the signaling pathways and mech...
ORGANISM(S): Homo sapiens (Human) 
2018-02-09 | PXD004255 | Pride
Uv Nelfe P38 Mk2 Phosphoproteomics 
GenomicsMK2/p38/p53 negatively regulate basal IL-1β and noncanonical NF-κB signaling
MK2/p38/p53 negatively regulate basal IL-1β and noncanonical NF-κB signaling
PRJNA1272351 | ENA
GenomicsMK2 and MK3 regulate LPS-induced inflammatory response of macrophages [360min]
MK2 and MK3 regulate LPS-induced inflammatory response of macrophages [360min]
PRJNA507375 | ENA
GenomicsMK2 and MK3 regulate LPS-induced inflammatory response of macrophages [120min]
MK2 and MK3 regulate LPS-induced inflammatory response of macrophages [120min]
PRJNA507376 | ENA
GenomicsSchizophyllum fasciatum strain:CBS 267.60.MK2
Schizophyllum fasciatum CBS 267.60.MK2 Resequencing genome sequencing
PRJNA620486 | ENA
UnknownCytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2.
Not available
S-EPMC4979411 | biostudies-literature
TranscriptomicsMK2/p38/p53 negatively regulate basal IL-1β and noncanonical NF-κB signaling
Interleukin (IL)-1β is a pro-inflammatory cytokine implicated in sterile inflammation and tumor development. Investigating the role of MAPKAP kinase 2 (MK2) in IL-1β processing, we found that Il1b mRNA and IL-1β protein levels were elevated in resting MK2-knockout (KO) macrophages and in the serum o...
ORGANISM(S): Mus musculus 
2026-04-02 | GSE299040 | GEO
TranscriptomicsWT and Mk2/3 KO MEFs response to etoposide
Primary mouse embryonic fibroblasts (MEFs) from wt and MK2/3 KO mice were treated with 20µM etoposide.
ORGANISM(S): Mus musculus 
2015-04-07 | GSE67266 | GEO
GenomicsCross species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation
Cross species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation
PRJNA690058 | ENA
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