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ModelsBaker2017 - The role of cytokines, MMPs and fibronectin fragments osteoarthritis
Baker2017 - The role of cytokines, MMPs and fibronectin fragments osteoarthritis This model is described in the article: Mathematical modelling of cytokines, MMPs and fibronectin fragments in osteoarthritic cartilage. Baker M, Br...
2024-09-02 | BIOMD0000000928 | BioModels
ProteomicsActive Site Specificity Profiling of the Matrix Metalloproteinase Family: Proteomic Identification of 4,300 Cleavage Sites by MMPs 1, 2, 3, 7, 8, 9, 12, 13, and 14.
Background: The active site of matrix metalloproteinases (MMPs) is highly conserved, complicating the rational design of specific substrates and inhibitors for individual family members. Results: Active site specificity profiles of 9 MMPs were determined using high throughput Proteomic Identificatio...
ORGANISM(S): Homo sapiens (Human) 
2015-09-29 | PXD002265 | Pride
Ecm Pics Mmps Mass spectrometry Specificity profiling Webpics 
ProteomicsATOMS determination of MMP cleavage site locations in YRS
Recombinant human tyrosyl-tRNA synthetase (YRS) was cleaved using recombinant MMPs. Terminal amine oriented mass spectrometry of substrates (ATOMS) was used to identify MMP generated cleavage sites from these mixtures with LC-MS/MS analysis.
ORGANISM(S): Homo sapiens (Human) 
2019-05-29 | PXD013366 | Pride
Mmp Protease Lc-ms/ms 
ProteomicsATOMS analyses of MMP cleavage sites in WRS
Human tryptophanyl-tRNA synthetase (WRS) was digested by human MMPs, and digestion mixtures were subjected to terminal amine oriented mass spectrometry of substrates (ATOMS) protocol and LC-MS/MS analysis to identify MMP cleavage sites in WRS.
ORGANISM(S): Homo sapiens (Human) 
2019-05-29 | PXD013367 | Pride
Mmp Protease Lc-ms/ms 
TranscriptomicsUpregulation of Expression of Matrix Metalloproteinases in Alveolar Macrophages of HIV1+ Smokers with Early Emphysema
HIV1+ smokers develop emphysema at an earlier age and with a higher incidence than HIV1- smokers. Based on the knowledge that human alveolar macrophages (AM) are capable of producing proteases that degrade extracellular matrix components, we hypothesized that upregulation of AM matrix metalloprotein...
ORGANISM(S): Homo sapiens 
2016-03-24 | E-GEOD-10038 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C57Bl6 MMP-7 and MMP-10 deficient mice Pseudomonas aeruginosa exposed airway epithelium.
Airway epithelium is the initial point of host-pathogen interaction in Pseudomonas aeruginosa infection, an important pathogen in cystic fibrosis and nosocomial pneumonia. We used global gene expression analysis to determine airway epithelial transcriptional responses dependent on matrilysin (MMP-7)...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7957 | biostudies-arrayexpress
UnknownMMPs-related risk model identification and SAA1 promotes clear cell renal cell carcinoma migration via ERK-AP1-MMPs axis.
Not available
S-EPMC11043417 | biostudies-literature
UnknownAssociation of Common Variants in MMPs with Periodontitis Risk.
Not available
S-EPMC4853955 | biostudies-literature
UnknownMMPs regulate both development and immunity in the tribolium model insect.
Not available
S-EPMC2649432 | biostudies-literature
UnknownExpression of matrix metalloproteinases (MMPs)-2/-7/-9/-14 and tissue inhibitors of MMPs (TIMPs)-1/-2 in bovine cutaneous fibropapillomas associated with BPV-2 infection.
Not available
S-EPMC9744227 | biostudies-literature
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