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ProteomicsMultifunctional polyphenol-based silk hydrogel alleviates oxidative stress and enhances endogenous regeneration of osteochondral defects
The native microenvironment following osteochondral defect is not permissive for its endogenous regeneration. A variety of hydrogels have been developed to regulate cell behaviors; however, there is still a lack of hydrogels with multifunctional properties that can provide a supportive microenvironm...
ORGANISM(S): Rattus Rattus 
2021-11-28 | PXD030026 |
ProteomicsSilk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation. Conventional strategies, such as the control of implant microstructure or the introduction of growth factors,...
ORGANISM(S): Rattus Norvegicus Mus Musculus 
2022-03-04 | PXD031852 |
ProteomicsThe influence of IL-1β and TNF-α on the tenogenic differentiation of human periodontal ligament stem cells via global proteomic analysis
The hPDLSCs were cultured in the tenogenic medium treated with 0.1 ng/ml IL-1β or 10 ng/ml TNF-α for 7 days. Total proteins were isolated from the collected cell samples. Subsequently, the LFQ-based proteomic analysis was conducted for the extracted proteins in each group as established procedures...
ORGANISM(S): Homo Sapiens 
2024-10-05 | PXD056585 |
ProteomicsThe data of protein expression of hMSCs in Soft, Medium and Stiff group
After treated with different stiffness and macrophage paracrine signals at the same stiffness for 3 days, MSCs were harvested for proteomic analysis. The label-free quantification (LFQ) based proteomic analysis was performed for global protein expressions.
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035511 |
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