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Through proteomic analysis comparing the abundance changes between knockout mutants of the two regulatory subunits of protein kinase MoCK2 and the wild-type Ku80 in Magnaporthe oryzae, this study reveals the underlying regulatory mechanisms by which the absence of MoCK2 leads to loss of pathogenicit...
ORGANISM(S): Pyricularia oryzae 70-15 
2025-10-07 | PXD066250 | Pride
In Magnaporthe oryzae, the protein kinase MoCK2 plays a crucial role in the pathogenicity of the fungus. Since knockout mutants of its regulatory subunits completely lose pathogenicity, analyzing differences in protein phosphorylation between mutants and wild-type strains and identifying proteins in...
ORGANISM(S): Pyricularia oryzae 70-15 
2025-10-07 | PXD066274 | Pride
Peste des petits ruminants virus (PPRV) infection causes highly contagious and severe disease in domestic and wild ruminants. It is widely reported that PRRV infection causes considerable innate immunosuppression in its host and promotes viral replication. However, how does the host rescue the innat...
ORGANISM(S): Ovis aries 
2021-07-26 | PXD022271 | Pride
Nucleophosmin (NPM1) is either frequently mutated or subjected to chromosomal translocation in acute myeloid leukemia (AML). NPM protein is primarily located in the nucleus, but the recurrent NPMc+ mutation is characterized by cytoplasmic localization and leukemogenic properties. Similarly, the NPM-...
ORGANISM(S): Homo sapiens (Human) 
2019-10-18 | PXD012305 | Pride
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