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ProteomicsNPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes
Nucleophosmin (NPM1) is either frequently mutated or subjected to chromosomal translocation in acute myeloid leukemia (AML). NPM protein is primarily located in the nucleus, but the recurrent NPMc+ mutation is characterized by cytoplasmic localization and leukemogenic properties. Similarly, the NPM-...
ORGANISM(S): Homo sapiens (Human) 
2019-10-18 | PXD012305 | Pride
Chromatin remodeling complexes Npm-mlf1 Leukemia Npm Proteomic Epigenetic 
GenomicsNPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes
NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes
PRJNA512203 | ENA
TranscriptomicsNPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes
Nucleophosmin (NPM1) is either frequently mutated or subjected to chromosomal translocation in acute myeloid leukemia (AML). NPM protein is primarily located in the nucleus, but the recurrent NPMc+ mutation is characterized by cytoplasmic localization and leukemogenic properties. Similarly, the NPM-...
ORGANISM(S): Homo sapiens 
2019-10-17 | GSE124495 | GEO
UnknownNPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes.
Not available
S-EPMC6853375 | biostudies-literature
UnknownShuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation.
Not available
S-EPMC2223285 | biostudies-literature
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